BDBM92620 Benzimidamide, 6b

SMILES: CCCCOc1cccc(c1)-c1cc(Oc2ccccc2)cc(c1)C(N)=N

InChI Key: InChIKey=ILNLXEHLDZXTBQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 92620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM92620 (Benzimidamide, 6b) Show SMILES CCCCOc1cccc(c1)-c1cc(Oc2ccccc2)cc(c1)C(N)=N Show InChI InChI=1S/C23H24N2O2/c1-2-3-12-26-21-11-7-8-17(14-21)18-13-19(23(24)25)16-22(15-18)27-20-9-5-4-6-10-20/h4-11,13-16H,2-3,12H2,1H3,(H3,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Health Science Center					Assay Description BACE1 inhibitory evaluation was carried out using a Fluorescence Resonance Energy Transfer (FRET) assay kit supplied by PanVera (kit P2985, Madison, ...				Chem Biol Drug Des 80: 775-80 (2012) Article DOI: 10.1111/cbdd.12016 BindingDB Entry DOI: 10.7270/Q2G73C93
					More data for this Ligand-Target Pair