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BDBM92620 Benzimidamide, 6b

SMILES: CCCCOc1cccc(c1)-c1cc(Oc2ccccc2)cc(c1)C(N)=N

InChI Key: InChIKey=ILNLXEHLDZXTBQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 92620   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-secretase 1


(Homo sapiens (Human))
BDBM92620
PNG
(Benzimidamide, 6b)
Show SMILES CCCCOc1cccc(c1)-c1cc(Oc2ccccc2)cc(c1)C(N)=N
Show InChI InChI=1S/C23H24N2O2/c1-2-3-12-26-21-11-7-8-17(14-21)18-13-19(23(24)25)16-22(15-18)27-20-9-5-4-6-10-20/h4-11,13-16H,2-3,12H2,1H3,(H3,24,25)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 7.03E+3n/an/an/an/an/an/a



Peking University Health Science Center



Assay Description
BACE1 inhibitory evaluation was carried out using a Fluorescence Resonance Energy Transfer (FRET) assay kit supplied by PanVera (kit P2985, Madison, ...


Chem Biol Drug Des 80: 775-80 (2012)


Article DOI: 10.1111/cbdd.12016
BindingDB Entry DOI: 10.7270/Q2G73C93
More data for this
Ligand-Target Pair