BDBM92787 WAG-003

SMILES CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCC[N+](C)(C)C)c(I)c1

InChI Key InChIKey=CPUKLBDTNMMBMC-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 92787   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Wisconsin

LigandPNGBDBM92787(WAG-003)
Affinity DataIC50:  3.00E+4nMAssay Description:IC50 values of aminodarone analogues using JARID1A PHD3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM92787(WAG-003)
Affinity DataIC50:  3.07E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7B (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Wisconsin

LigandPNGBDBM92787(WAG-003)
Affinity DataIC50:  1.66E+6nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from recombinant His6-tagged human KDM5A (PHD3) (1542 to 1660 residues) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 7A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM92787(WAG-003)
Affinity DataIC50:  2.23E+6nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7A (PHD-JmjC) (unknown origin) preincubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM92787(WAG-003)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of recombinant HQ5-Halo-tagged KDM4A tudor domain (unknown origin) measured by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase PHF2(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM92787(WAG-003)
Affinity DataIC50:  9.76E+5nMAssay Description:Displacement of C-terminally biotinylated-H3K4me3 (1 to 21 residues) peptide from KDM7C (PHD) (unknown origin) preincubated for 15 mins followed by p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Wisconsin

LigandPNGBDBM92787(WAG-003)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of recombinant HQ5-Halo-tagged JARID1A PHD3 finger domain (unknown origin) expressed in BL21(DE3)pLysS cells after 1 hr by chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Wisconsin

LigandPNGBDBM92787(WAG-003)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of recombinant HQ5-Halo-tagged KDM5A PHD3 domain (unknown origin) measured by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Wisconsin

LigandPNGBDBM92787(WAG-003)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of H3K4me3 binding to Halo-tagged GST-fused KDM5A PHD3 domain (unknown origin) expressed in Escherichia coli by HaloTag-based peptide di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed