BDBM92871 4-Aminoquinazoline derivative, 6f

SMILES CCOC(=O)c1csc2cc(Nc3ncnc4cc(OCCCN5CCN(C)CC5)ccc34)ccc12

InChI Key InChIKey=WZSQZESQWZLUNN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92871   

TargetAurora kinase B(Homo sapiens (Human))
Southeast University

LigandPNGBDBM92871(4-Aminoquinazoline derivative, 6f)
Affinity DataIC50:  136nMAssay Description:The kinase assay of Aurora A and B was measured using HTRF-kinEASE-STK discovery kit purchased from Cisbio.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Southeast University

LigandPNGBDBM92871(4-Aminoquinazoline derivative, 6f)
Affinity DataIC50:  111nMAssay Description:The kinase assay of Aurora A and B was measured using HTRF-kinEASE-STK discovery kit purchased from Cisbio.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed