BDBM93624 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrid[4,3-b]indol-1-one;hydrochloride::5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one;hydrochloride::ALOSETRON::ALOSETRON HCl::MLS001401464::SMR000469211::cid_60758

SMILES Cc1nc[nH]c1CN1CCc2c(C1=O)c1ccccc1n2C

InChI Key InChIKey=JSWZEAMFRNKZNL-UHFFFAOYSA-N

Data  2 KI  10 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 93624   

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
TargetSentrin-specific protease 8(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataIC50:  7.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataIC50:  3.24E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by whole cell patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataIC50:  3.24E+3nMAssay Description:Inhibition of human Potassium channel HERG expressed in mammalian cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataIC50:  3.24E+3nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSentrin-specific protease 8(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataIC50:  7.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM93624(5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed