BDBM9426 CHEMBL258928::Heterodimeric Tacrine-Based Inhibitor 5g::N-(8-aminooctyl)-1,2,3,4-tetrahydroacridin-9-amine dihydrochloride::N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octane Bis-hydrochloride

SMILES: NCCCCCCCCNc1c2CCCCc2nc2ccccc12

InChI Key: InChIKey=LFBAUYQQFKFFCF-UHFFFAOYSA-N

Data: 8 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 9426   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Rat)	BDBM9426 (N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	89.4	n/a	n/a	n/a	n/a	7.4	37
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Carboxylic ester hydrolase (Rat)	BDBM9426 (N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM9426 (N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Electric eel)	BDBM9426 (N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
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Carboxylic ester hydrolase (Horse)	BDBM9426 (N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Rat)	BDBM9426 (N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Horse)	BDBM9426 (N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM9426 (N-9-(1,2,3,4-Tetrahydroacridinyl)-1,8-diamino-octa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair