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BDBM97695 US8476255, 55

SMILES: CSc1ccc(\C=C(\C(=O)NCc2ccc(cc2)C(=O)NO)c2cccnc2)cc1

InChI Key: InChIKey=CZIFWUIZPKVGJZ-FYJGNVAPSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97695   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 1


(Mus musculus (Mouse))
BDBM97695
PNG
(US8476255, 55)
Show SMILES CSc1ccc(\C=C(\C(=O)NCc2ccc(cc2)C(=O)NO)c2cccnc2)cc1
Show InChI InChI=1S/C23H21N3O3S/c1-30-20-10-6-16(7-11-20)13-21(19-3-2-12-24-15-19)23(28)25-14-17-4-8-18(9-5-17)22(27)26-29/h2-13,15,29H,14H2,1H3,(H,25,28)(H,26,27)/b21-13+
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MMDB

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Similars

US Patent
n/an/a 20n/an/an/an/an/a37



Orchid Chemicals & Pharmaceuticals Limited

US Patent


Assay Description
Histone Deacetylase (HDAC) inhibition assay using Boc-Lys (Ac)-AMC substrate. The fluorometric assay provides a fast and fluorescence based method t...


US Patent US8476255 (2013)


BindingDB Entry DOI: 10.7270/Q27S7MCR
More data for this
Ligand-Target Pair