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BDBM9784 (2S)-6-[(2S)-2-amino-3-phenylpropanamido]-2-[(4-methylbenzene)(2-methylpropyl)sulfonamido]hexanoic acid::Lysine Sulfonamide 11u

SMILES: CC(C)CN([C@@H](CCCCNC(=O)[C@@H](N)Cc1ccccc1)C(O)=O)S(=O)(=O)c1ccc(C)cc1

InChI Key: InChIKey=DCNBOHVQLTUPPO-ZEQRLZLVSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9784   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HIV-1 Protease


(Human immunodeficiency virus type 1)
BDBM9784
PNG
((2S)-6-[(2S)-2-amino-3-phenylpropanamido]-2-[(4-me...)
Show SMILES CC(C)CN([C@@H](CCCCNC(=O)[C@@H](N)Cc1ccccc1)C(O)=O)S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C26H37N3O5S/c1-19(2)18-29(35(33,34)22-14-12-20(3)13-15-22)24(26(31)32)11-7-8-16-28-25(30)23(27)17-21-9-5-4-6-10-21/h4-6,9-10,12-15,19,23-24H,7-8,11,16-18,27H2,1-3H3,(H,28,30)(H,31,32)/t23-,24-/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.5n/an/an/an/an/an/an/an/a



Pharmacor Inc



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...


Bioorg Med Chem Lett 13: 4289-92 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.058
BindingDB Entry DOI: 10.7270/Q26H4FN2
More data for this
Ligand-Target Pair