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BDBM98244 US8481733, 56

SMILES: Nc1nccn2c(nc(-c3ccc(CC4CCCCO4)cc3)c12)C1CCC1

InChI Key: InChIKey=RTJLPJXDPRBODG-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98244   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine kinase non-receptor protein 2


(Homo sapiens (Human))
BDBM98244
PNG
(US8481733, 56)
Show SMILES Nc1nccn2c(nc(-c3ccc(CC4CCCCO4)cc3)c12)C1CCC1
Show InChI InChI=1/C22H26N4O/c23-21-20-19(25-22(17-4-3-5-17)26(20)12-11-24-21)16-9-7-15(8-10-16)14-18-6-1-2-13-27-18/h7-12,17-18H,1-6,13-14H2,(H2,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.78E+3n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

US Patent


Assay Description
AlphaScreen (amplified luminescent proximity homogeneous assay) assay was used to test for ACK1 inhibitory activity.


US Patent US8481733 (2013)


BindingDB Entry DOI: 10.7270/Q2XD109J
More data for this
Ligand-Target Pair