BDBM98586 (2R)-2-[[4-(aminomethyl)phenyl]methylsulfonylamino]-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-oxo-ethyl]-3-hydroxy-propanamide::US8476306, 6.11

SMILES NCc1ccc(CS(=O)(=O)N[C@H](CO)C(=O)NCC(=O)NCc2ccc(cc2)C(N)=N)cc1

InChI Key InChIKey=XTINWPDNJKDTDS-GOSISDBHSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98586   

TargetUrokinase plasminogen activator surface receptor(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98586((2R)-2-[[4-(aminomethyl)phenyl]methylsulfonylamino...)
Affinity DataKi:  120nM ΔG°:  -9.40kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against Plasminogen activator urokinaseMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98586((2R)-2-[[4-(aminomethyl)phenyl]methylsulfonylamino...)
Affinity DataKi:  280nM ΔG°:  -8.90kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against TrypsinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98586((2R)-2-[[4-(aminomethyl)phenyl]methylsulfonylamino...)
Affinity DataKi:  7.40E+3nM ΔG°:  -6.97kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98586((2R)-2-[[4-(aminomethyl)phenyl]methylsulfonylamino...)
Affinity DataKi:  8.00E+3nM ΔG°:  -6.93kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent