BDBM98597 (2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-oxo-ethyl]-2-[(3,4-dichlorophenyl)methylsulfonylamino]-3-hydroxy-propanamide::US8476306, 6.23

SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccc(Cl)c(Cl)c2)cc1

InChI Key InChIKey=ITGOAPKQQWGASV-QGZVFWFLSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98597   

TargetUrokinase plasminogen activator surface receptor(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98597((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  110nM ΔG°:  -9.45kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against Plasminogen activator urokinaseMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98597((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  600nM ΔG°:  -8.45kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against TrypsinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98597((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  8.30E+3nM ΔG°:  -6.90kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98597((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)
Affinity DataKi:  3.20E+4nM ΔG°:  -6.11kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In DepthDetails US Patent