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BDBM98703 US8497288, 32

SMILES: FC(F)(F)Oc1ccc(cc1)N1C[C@@H]2C[C@H](CN2C1=O)NS(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=BGQYBFTWRQLWPH-UYWMCZCJNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98703   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hormone-sensitive lipase (HSL)


(Homo sapiens (Human))
BDBM98703
PNG
(US8497288, 32)
Show SMILES FC(F)(F)Oc1ccc(cc1)N1C[C@@H]2C[C@H](CN2C1=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1/C19H17ClF3N3O4S/c20-12-1-7-17(8-2-12)31(28,29)24-13-9-15-11-26(18(27)25(15)10-13)14-3-5-16(6-4-14)30-19(21,22)23/h1-8,13,15,24H,9-11H2/t13-,15+/s2
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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 362n/an/an/an/an/an/a



Hoffmann-La Roche Inc

US Patent


Assay Description
Human hormone-sensitive lipase (HSL) enzyme assay: HSL enzyme activity was measured by a colorimetic assay.


US Patent US8497288 (2013)


BindingDB Entry DOI: 10.7270/Q23X8590
More data for this
Ligand-Target Pair