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BDBM99071 US8497265, 777

SMILES: Cc1cccnc1C(=O)N1CCC(CC1)Oc1ncccc1C1CCOCC1

InChI Key: InChIKey=HDNMLTDURTYHKA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99071   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase Type 10 (PDE10A)


(Rattus norvegicus (rat))
BDBM99071
PNG
(US8497265, 777)
Show SMILES Cc1cccnc1C(=O)N1CCC(CC1)Oc1ncccc1C1CCOCC1
Show InChI InChI=1S/C22H27N3O3/c1-16-4-2-10-23-20(16)22(26)25-12-6-18(7-13-25)28-21-19(5-3-11-24-21)17-8-14-27-15-9-17/h2-5,10-11,17-18H,6-9,12-15H2,1H3
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MMDB

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PC sid
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Similars

US Patent
n/an/a 1.00E+3n/an/an/an/an/an/a



Amgen Inc.

US Patent


Assay Description
Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).


US Patent US8497265 (2013)


BindingDB Entry DOI: 10.7270/Q2VD6X39
More data for this
Ligand-Target Pair