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BDBM99089 US8497265, 795

SMILES: O=C(N1CC(C1)Oc1cnccn1)c1nc2ccccc2[nH]1

InChI Key: InChIKey=UTMXRFCMUGSIKY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99089   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase Type 10 (PDE10A)


(Rattus norvegicus (rat))
BDBM99089
PNG
(US8497265, 795)
Show SMILES O=C(N1CC(C1)Oc1cnccn1)c1nc2ccccc2[nH]1
Show InChI InChI=1S/C15H13N5O2/c21-15(14-18-11-3-1-2-4-12(11)19-14)20-8-10(9-20)22-13-7-16-5-6-17-13/h1-7,10H,8-9H2,(H,18,19)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.23E+4n/an/an/an/an/an/a



Amgen Inc

US Patent


Assay Description
Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).


US Patent US8497265 (2013)


BindingDB Entry DOI: 10.7270/Q2VD6X39
More data for this
Ligand-Target Pair