BDBM99537 CHEMBL2062804::US8501936, 35

SMILES: CN1CCN(CC1)c1cccc(Nc2nc3c(cccn3n2)-c2ccc(cc2)S(C)(=O)=O)c1

InChI Key: InChIKey=RFZKSQIFOZZIAQ-UHFFFAOYSA-N

Data: 11 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 99537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Human)	BDBM99537 (CHEMBL2062804 | US8501936, 35) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM99537 (CHEMBL2062804 | US8501936, 35) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM99537 (CHEMBL2062804 | US8501936, 35) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84.7	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM99537 (CHEMBL2062804 | US8501936, 35) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	202	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM99537 (CHEMBL2062804 | US8501936, 35) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK1 (Human)	BDBM99537 (CHEMBL2062804 | US8501936, 35) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM99537 (CHEMBL2062804 | US8501936, 35) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK1 (Human)	BDBM99537 (CHEMBL2062804 | US8501936, 35) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM99537 (CHEMBL2062804 | US8501936, 35) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM99537 (CHEMBL2062804 | US8501936, 35) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM99537 (CHEMBL2062804 | US8501936, 35) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM99537 (CHEMBL2062804 | US8501936, 35) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair