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BDBM99971 US8501750, 149

SMILES: CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(O)C(C)(C)C)c2=O

InChI Key: InChIKey=RZKLMAYXHYZWLN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99971   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))
BDBM99971
PNG
(US8501750, 149)
Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(O)C(C)(C)C)c2=O
Show InChI InChI=1S/C29H30N4O5S/c1-5-19-14-22-25(35)32(16-23(34)29(2,3)4)28(37)33(26(22)39-19)15-17-10-12-18(13-11-17)20-8-6-7-9-21(20)24-30-27(36)38-31-24/h6-14,23,34H,5,15-16H2,1-4H3,(H,30,31,36)
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PC sid
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Similars

US Patent
n/an/a 1.80n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
Binding assay using human AT1.


US Patent US8501750 (2013)


BindingDB Entry DOI: 10.7270/Q2F76B5Q
More data for this
Ligand-Target Pair