BindingDB Entity Report

 

 

Entity Name

Entity Definition

Entity Attribute Name

Entity Attribute Definition

ART_AUT

This table associates authors (PERSON) with articles (ARTICLE)

ARTICLEID

Automatically generated integer ID for an article.  This may be an article in the on-line Journal associated with this database.

AUTHORID

Person ID, see PERSON table

LASTNAME

Last name of an author of this article. (Required)

FIRSTNAME

First name of an author of this article. (Required)

AUTH_SEQ

Ordinal sequence number of this author in the articles author list.

CONTACT

"Yes" for the corresponding author of the paper.

ARTICLE

This table contains articles that are referenced by Entry.

JOURNALID

ID of the journal of publication; see JOURNAL table.

ARTICLEID

Automatically generated integer ID for an article. This may be an article in the on-line journal associated with this database.

TITLE

The full title of this scientific publication.

PMID

PubMed reference ID of this article.

VOLUME

Volume of journal in which article was published. Must be a number; expressions like (23) or 21-2 are invalid.

YEAR

Year of publication; must be a four-digit number.

FIRSTPAGE

Page number of the first page of the article.

LASTPAGE

Page number of the last page of the article.

ABSTRACT

Abstract of the article.

ARTICLE_KWORD

This table contains keywords describing an article. One Article ID may relate to several keywords.

ARTICLEID

ARTICLE ID of the article for which keywords are listed.

KWORD

Keywords that describe an article.

ASSAY

Text description of enzyme-inhibition assay method.

ASSAYID

Automatically generated integer ID for this assay.

ASSAY_NAME

The full name of the assay.

DESCRIPTION

Detailed text description of the assay

COMPLEX

Table of molecules consisting of more than one component.

COMPLEXID

Automatically generated integer ID for each complex.

TYPE

The "type" of the Complex. This is usually drawn usually from the following (preliminary) enumerated list, but a user-specified type is also allowed. 1) Protein Complex 2) DNA Complex 3) RNA Complex 4) Other Complex

WEIGHT

Molecular mass of this complex, in g/mol.

DISPLAY_NAME

The most commonly used name of the complex

COMPONENT_COUNT

The number components making up this complex

COMMENTS

Any description of the complex that is not covered by the other attributes.

COMPLEX_COMPONENT

Table listing the Monomer(s) and Polymer(s) that compose a Complex.

COMPLEXID

The ID of the Complex to which this component belongs.

COMPONENTID

The ID of this component.

POLYMERID

The ID of a Polymer included in this complex (See POLYMER table.)

MONOMERID

The ID of a Monomer included in this complex (See MONOMER table.)

TYPE

The "type" of the component, a monomer or polymer

COMPLEX_NAME

Table storing the synonyms for a complex.

COMPLEXID

ID of the complex to which names apply.

NAME

A legitimate name of a Complex; e.g., "Ca Binding protein with Ca++ ". For compounds without an obvious name, a corporate or other ID can be used.

DATA_FIT_METH

Table storing the data fitting methods used in analyzing binding results.

DATA_FIT_METH_ID

Automatically generated integer ID for each data fitting method.

DATA_FIT_METH_DESC

Free text description of the method used to fit the experimental data to the reaction model.

DATA_FIT_SOFTWARE

Identity of the computer software, if any, used in fitting experimental data to the reaction model.

SOFTWARE_VERSION

The version number of the computer software.

COMMENTS

Further description of the data fitting method.

ENTRY

Table with summary information for each BindingDB data entry.  An entry contains a set of related data. It may contain one or more binding reaction results and one or more citations.

ENTRYID

Automatically generated integer ID for an entry.

ENTRYTITLE

Descriptive title of an entry in the binding database. The title should normally include a brief description of the molecules involved, the technique used, and the type of solvent, along with any other notable features of the study.

MEAS_TECH

The measurement technique used in this entry. e.g. ITC, KI.

HOLD

"Yes" if entrant wishes this entry to be held rather than released as soon as possible.

REVISED

In order to keep a record of data revisions, direct modification of an existing entry is not allowed. Instead, a new entry is created based upon the original, and the original is removed from the LOOKUP table (see below).  "Yes" in the Revised attribute implies that the entry is a revised version of an older entry.

DEPOID

The unique deposition ID assigned at deposition time.

COMMENTS

Free text comments on this entry.

ENTRYDATE

The date when this entry was entered or last updated.

ENTRANTID

The PersonID of the Entrant-- the person who entered these data.

ENTRY_CITATION

Table associating an entry with the appropriate journal citations.

ENTRYID

Entry ID; see ENTRY table.

ARTICLEID

Article ID of an article linked with this entry.

ART_PURP

Key word describing the main reason this article is cited along with this BindingDB entry. For example, if this article contains the actual binding measurements, the reason would be "Binding Data". If the paper contains the method used for the measurements, but not the data, then "Method" would be appropriate here. The Reason for Citation is drawn from an enumerated list that includes the following: 1) Binding Data 2) Background 3) Method 4) Molecule information 5) DNA sequence 6) Protein sequence 7) Structure 8) Synthesis

ENTRY_KWORD

Table storing keywords that describes an entry.

ENTRYID

Entry ID of the entry associated with this keyword.

KWORD

Words or phrases describing this entry, to facilitate retrieval by database users.

ENZYME_REACTANT_SET

Table storing the list of reactants -- enzyme, substrate and inhibitor --  that are involved in binding measurement by enzyme inhibition. 

ENTRYID

Entry ID, see ENTRY table.

REACTANT_SET_ID

Automatically generated integer ID for a KI reactant set.

INHIBITOR

Common name of the inhibitor for initial display.

I_MONOMERID

If the inhibitor is a monomer, this is its link to the MONOMER table; I_POLYMERID and I_COMPLEXID will then be null.

I_POLYMERID

If the inhibitor is a polymer, this is its link to POLYMER table; I_MONOMERID and I_COMPLEXID will then be null.

I_COMPLEXID

If the inhibitor is a complex, this is its link to COMPLEX table; I_POLYMERID and I_MONOMERID will then be null.

ENZYME

Common name of the enzyme for initial display.

E_POLYMERID

If the enzyme is a single-chain polymer, this is its link to POLYMER table; E_COMPLEXID will be null.

E_COMPLEXID

If the enzyme is a complex, this is its link to COMPLEX table; E_POLYMERID will be null.

SUBSTRATE

Common name of the substrate for initial display.

S_MONOMERID

Same as I_MONOMERID, for substrate.

S_COMPLEXID

Same as I_COMPLEXID, for substrate.

S_POLYMERID

Same as I_POLYMERID, for substrate.

COMMENTS

Free text comments on this enzyme reactant set.

INSTRUMENT

Table describing the instrument used in this study

INSTRUMENTID

Automatically generated integer ID for an instrument.

TYPE

Type of the instrument used in the binding reaction. e.g. microcalorimeter.

MODEL

The name of the model of the instrument, if applicable.

MANUFACT

Name of the instrument manufacturer, if applicable.

YEAR

The model year of the instrument, or the year it was constructed.

COMMENTS

Further description of the instrument.

ITC_RESULT_A_B_AB

Table storing the thermodynamic results of one ITC binding experiment interpreted using the model A+B=AB.

ENTRYID

Entry ID, see ENTRY table.

ITC_RESULT_A_B_AB_ID

Automatically generated integer ID for an A+B=AB reaction.

CELL_COMPLEXID

If the cell reactant is a complex, this is its link to COMPLEX table. CELL_POLYMERID and CELL_MONOMERID will be null.

CELL_MONOMERID

If the cell reactant is a monomer, this is its link to COMPLEX table. CELL_POLYMERID and CELL_COMPLEXID will be null.

CELL_POLYMERID

If the cell reactant is a polymer, this is its link to POLYMER table. CELL_COMPLEXID and CELL_MONOMERID will be null.

CELL_REACT

Name of the binding reactant in the calorimeter's cell (reaction vessel).

CELL_REACT_SOURCE

Brief description of the source (e.g., chemical supplier) of this cell reactant.

CELL_REACT_PURITY

The purity of this cell reactant, in percentage, grade, etc.

CELL_REACT_PREP_METH

Brief description of how the cell reactant is prepared, if appropriate.

SYR_REACT

The name of the binding reactant in the injection syringe.

SYR_MONOMERID

If the syringe reactant is a monomer, this is its link to the MONOMR table. SYR_POLYMERID and SYR_COMPLEXID will be null.

SYR_POLYMERID

If the syringe reactant is a polymer, this is its link to POLYMER table. SYR_COMPLEXID and SYR_MONOMERID will be null.

SYR_COMPLEXID

If the syringe reactant is a complex, this is its link to COMPLEX table. CELL_POLYMERID and CELL_MONOMERID will be null.

SYR_REACT_SOURCE

Brief description of the source of this syringe reactant; e.g., chemical supplier.

SYR_REACT_PURITY

The purity of this syringe reactant, in percentage, grade, etc.

SYR_REACT_PREP_METH

Brief description of how the syringe reactant is prepared, if appropriate.

PH

The solution pH for which these reported results apply.

PH_UNCERT

The reported uncertainty in the pH.

TEMP

The temperature for which these thermodynamic results are reported, in unit of  °C

TEMP_UNCERT

The uncertainty in the temperature.

PRESS

The pressure for which these results are reported; typically 1 atmosphere.

PRESS_UNCERT

The reported uncertainly in the pressure, in same units.

ION_STR

The reported ionic strength at which the measurements were made, in units of millimoles/liter.

ION_STR_UNCERT

The reported uncertainty in the ionic strength, in the same units.

STOICH_FREE_PARAM

"Yes" if the stoichiometry parameter is fixed by the user during the fit to the reaction model, and "no" if the stoichiometry is treated as a free parameter.

STOICH_PARAM

The stoichiometry of the binding reaction, defined as the molar ratio of the syringe reactant to the cell reactant at the midpoint of the binding isotherm. This can either be a fitted result, and thus possibly non-integer, or a fixed parameter. (See above item.)

FIT_SD

The reported standard deviation of the fit of the data to the reaction model in the data fitting procedure.