TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Inhibition of Aurora B/INCENP (unknown origin) assessed as affinity constant pre-incubated for 1 hr followed by FL-PKAtide substrate and ATP additionMore data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Inhibition of human Aurora B/INCENP pre-incubated for 30 mins before 5-FAM-PKAtide substrate addition and measured after 120 minsMore data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 5.50E+3nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 7.40E+3nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 1.29E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 1.51E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 1.87E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 2.57E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 3.29E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 4.10E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 4.17E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 5.93E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 6.39E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 7.03E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 9.72E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 1.03E+5nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataKi: 1.60E+5nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of Aurora B/INCENP (unknown origin) pre-incubated for 1 hr followed by FL-PKAtide substrate and ATP additionMore data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Binding affinity towards [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in HG108-15More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair