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Found 12 Enz. Inhib. hit(s) with Target = 'Cyclin-K/Cyclin-dependent kinase 9'
TargetCyclin-K/Cyclin-dependent kinase 9(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525738(US11174252, Compound 33)
Affinity DataIC50:  2nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-K/Cyclin-dependent kinase 9(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525743(US11174252, Compound 38)
Affinity DataIC50:  2nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-K/Cyclin-dependent kinase 9(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525729(US11174252, Compound 24)
Affinity DataIC50:  4nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-K/Cyclin-dependent kinase 9(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525750(US11174252, Compound 437)
Affinity DataIC50:  4nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-K/Cyclin-dependent kinase 9(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525730(US11174252, Compound 25)
Affinity DataIC50:  5nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-K/Cyclin-dependent kinase 9(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  13nMAssay Description:Inhibition of CDK9/Cyclin K (unknown origin)-mediated phosphorylation of peptide substrate incubated for 15 mins prior to substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-K/Cyclin-dependent kinase 9(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525755(US11174252, Compound 442)
Affinity DataIC50:  41nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-K/Cyclin-dependent kinase 9(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525749(US11174252, Compound 436)
Affinity DataIC50:  73nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-K/Cyclin-dependent kinase 9(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525760(US11174252, Compound 447)
Affinity DataIC50:  243nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-K/Cyclin-dependent kinase 9(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525759(US11174252, Compound 446)
Affinity DataIC50:  280nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-K/Cyclin-dependent kinase 9(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM50263013(CHEMBL4079206)
Affinity DataIC50:  412nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using YSPTSPSYSPTSPSYSPTSPKKK as substrate after 30 mins in presence of [33P]-gamma-ATP by filter bindi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-K/Cyclin-dependent kinase 9(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM50526803(CHEMBL4434871 | US10870651, Compound 101)
Affinity DataIC50: >1.00E+3nMAssay Description:Compounds of the invention were assayed for activity against a variety of different kinases.More data for this Ligand-Target Pair
In DepthDetails US Patent