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Found 6 Enz. Inhib. hit(s) with Target = 'Integrin alpha-1/beta-1'
TargetIntegrin alpha-1/beta-1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50446804(CHEMBL3115061)
Affinity DataIC50:  33nMAssay Description:Antagonist activity at integrin alpha1beta1 receptor (unknown origin) assessed as inhibition of interaction with biotinylated collagen type-1 after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-1/beta-1 [T112H](Homo sapiens (Human))
University Of Pennsylvania

LigandPNGBDBM19057((2S)-3-({[(4-aminophenyl)methyl]carbamoyl}amino)-2...)
Affinity DataAssay Description:The ligand was immobilized on 96-well flat microtiter in PBS buffer solution overnight, and the wells were blocked with 1% BSA in HBSS buffer solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-1/beta-1 [T112H](Homo sapiens (Human))
University Of Pennsylvania

LigandPNGBDBM19066((2S)-3-[(benzylcarbamoyl)amino]-2-{[(2S)-1-[(3,5-d...)
Affinity DataAssay Description:The ligand was immobilized on 96-well flat microtiter in PBS buffer solution overnight, and the wells were blocked with 1% BSA in HBSS buffer solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-1/beta-1 [T112H](Homo sapiens (Human))
University Of Pennsylvania

LigandPNGBDBM19068((2S)-3-[(benzylcarbamoyl)amino]-2-{[(2S)-1-(naphth...)
Affinity DataAssay Description:The ligand was immobilized on 96-well flat microtiter in PBS buffer solution overnight, and the wells were blocked with 1% BSA in HBSS buffer solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-1/beta-1 [T112H](Homo sapiens (Human))
University Of Pennsylvania

LigandPNGBDBM19053((2S)-2-{[(2R)-1-(benzenesulfonyl)pyrrolidin-2-yl]f...)
Affinity DataAssay Description:The ligand was immobilized on 96-well flat microtiter in PBS buffer solution overnight, and the wells were blocked with 1% BSA in HBSS buffer solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-1/beta-1 [T112H](Homo sapiens (Human))
University Of Pennsylvania

LigandPNGBDBM19063((2S)-3-[(benzylcarbamoyl)amino]-2-{[(2S)-1-[(3,5-d...)
Affinity DataAssay Description:The ligand was immobilized on 96-well flat microtiter in PBS buffer solution overnight, and the wells were blocked with 1% BSA in HBSS buffer solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed