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Found 42 Enz. Inhib. hit(s) with Target = 'Phenylalanine--tRNA ligase alpha subunit'
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140706(5-(3,4-dichlorophenyl)-3-phenyl-(3R,3aR,6aS)-spiro...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140706(5-(3,4-dichlorophenyl)-3-phenyl-(3R,3aR,6aS)-spiro...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140709(5'-(3,4-dichlorophenyl)-3'-phenyl-(3'R,3a'S,6a'R)-...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140709(5'-(3,4-dichlorophenyl)-3'-phenyl-(3'R,3a'S,6a'R)-...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140707(5-(3-chloro-4-methylphenyl)-3-phenyl-(3R,3aS,6aR)-...)
Affinity DataIC50:  70nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140707(5-(3-chloro-4-methylphenyl)-3-phenyl-(3R,3aS,6aR)-...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140706(5-(3,4-dichlorophenyl)-3-phenyl-(3R,3aR,6aS)-spiro...)
Affinity DataIC50:  560nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140716(5'-(3-chloro-4-methylphenyl)-3'-phenyl-(3'R,3a'S,6...)
Affinity DataIC50:  730nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140706(5-(3,4-dichlorophenyl)-3-phenyl-(3R,3aR,6aS)-spiro...)
Affinity DataIC50:  850nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140717(5-benzo[d][1,3]dioxol-5-yl-3-phenylspiro[perhydrof...)
Affinity DataIC50:  970nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140716(5'-(3-chloro-4-methylphenyl)-3'-phenyl-(3'R,3a'S,6...)
Affinity DataIC50:  990nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140705(5-(2-methoxyphenyl)-3-phenylspiro[perhydrofuro[3,4...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140717(5-benzo[d][1,3]dioxol-5-yl-3-phenylspiro[perhydrof...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140709(5'-(3,4-dichlorophenyl)-3'-phenyl-(3'R,3a'S,6a'R)-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140709(5'-(3,4-dichlorophenyl)-3'-phenyl-(3'R,3a'S,6a'R)-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140705(5-(2-methoxyphenyl)-3-phenylspiro[perhydrofuro[3,4...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140716(5'-(3-chloro-4-methylphenyl)-3'-phenyl-(3'R,3a'S,6...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140713(4-benzoyl-2-(3,4-dichlorophenyl)-6-phenyl-(3aR,6R,...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140707(5-(3-chloro-4-methylphenyl)-3-phenyl-(3R,3aS,6aR)-...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140716(5'-(3-chloro-4-methylphenyl)-3'-phenyl-(3'R,3a'S,6...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140708(5-(2-methoxyphenyl)-3-(2-methylphenyl)-(3R,3aS,6aR...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140707(5-(3-chloro-4-methylphenyl)-3-phenyl-(3R,3aS,6aR)-...)
Affinity DataIC50:  1.37E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140713(4-benzoyl-2-(3,4-dichlorophenyl)-6-phenyl-(3aR,6R,...)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140713(4-benzoyl-2-(3,4-dichlorophenyl)-6-phenyl-(3aR,6R,...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140704(5-(4-chloro-3-trifluoromethylphenyl)-3-phenyl-(3R,...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140704(5-(4-chloro-3-trifluoromethylphenyl)-3-phenyl-(3R,...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140708(5-(2-methoxyphenyl)-3-(2-methylphenyl)-(3R,3aS,6aR...)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140713(4-benzoyl-2-(3,4-dichlorophenyl)-6-phenyl-(3aR,6R,...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140720(5-(4-nitrophenyl)-3-phenyl-(3R,3aS,6aR)-spiro[perh...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140722(5-benzo[d][1,3]dioxol-5-yl-3-(4-methylphenyl)-(3R,...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140711(5'-(3,4-dichlorophenyl)-3'-phenyl-(3'R,3a'R,6a'S)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140711(5'-(3,4-dichlorophenyl)-3'-phenyl-(3'R,3a'R,6a'S)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140722(5-benzo[d][1,3]dioxol-5-yl-3-(4-methylphenyl)-(3R,...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140720(5-(4-nitrophenyl)-3-phenyl-(3R,3aS,6aR)-spiro[perh...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140723(5-(4-methoxyphenyl)-3-phenyl-(3R,3aS,6aR)-spiro[pe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140714(CHEMBL27142 | methyl 5-(3,4-dichlorophenyl)-4,6-di...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140711(5'-(3,4-dichlorophenyl)-3'-phenyl-(3'R,3a'R,6a'S)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140715(3-(4-chlorophenyl)-5-(4-chloro-3-trifluoromethylph...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140714(CHEMBL27142 | methyl 5-(3,4-dichlorophenyl)-4,6-di...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140715(3-(4-chlorophenyl)-5-(4-chloro-3-trifluoromethylph...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140711(5'-(3,4-dichlorophenyl)-3'-phenyl-(3'R,3a'R,6a'S)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140723(5-(4-methoxyphenyl)-3-phenyl-(3R,3aS,6aR)-spiro[pe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed