KEGG   Homo sapiens (human): 5646
Entry
5646              CDS       T01001                                 
Symbol
PRSS3, MTG, PRSS4, T9, TRY3, TRY4
Name
(RefSeq) serine protease 3
  KO
K01312  trypsin [EC:3.4.21.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04972  Pancreatic secretion
hsa04974  Protein digestion and absorption
hsa05164  Influenza A
Drug target
Ulinastatin: D05183<JP>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5646 (PRSS3)
 09150 Organismal Systems
  09154 Digestive system
   04972 Pancreatic secretion
    5646 (PRSS3)
   04974 Protein digestion and absorption
    5646 (PRSS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    5646 (PRSS3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    5646 (PRSS3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5646 (PRSS3)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.4  trypsin
     5646 (PRSS3)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   5646 (PRSS3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   5646 (PRSS3)
SSDB
Motif
Pfam: Trypsin DUF1986
Other DBs
NCBI-GeneID: 5646
NCBI-ProteinID: NP_001184026
OMIM: 613578
HGNC: 9486
Ensembl: ENSG00000010438
UniProt: P35030 Q7Z5F4
Structure
Position
9:33750679..33799231
AA seq 261 aa
MHMRETSGFTLKKGRSAPLVFHPPDALIAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSH
FCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDN
DIMLIKLSSPAVINARVSTISLPTTPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVL
TQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRP
GVYTKVYNYVDWIKDTIAANS
NT seq 786 nt   +upstreamnt  +downstreamnt
atgcacatgagagagacaagtggcttcacattgaagaaggggaggagtgcgccattggtt
ttccatcctccagatgcactgattgctgtcccctttgacgatgatgacaagattgttggg
ggctacacctgtgaggagaattctctcccctaccaggtgtccctgaattctggctcccac
ttctgcggtggctccctcatcagcgaacagtgggtggtatcagcagctcactgctacaag
acccgcatccaggtgagactgggagagcacaacatcaaagtcctggaggggaatgagcag
ttcatcaatgcggccaagatcatccgccaccctaaatacaacagggacactctggacaat
gacatcatgctgatcaaactctcctcacctgccgtcatcaatgcccgcgtgtccaccatc
tctctgcccaccacccctccagctgctggcactgagtgcctcatctccggctggggcaac
actctgagctttggtgctgactacccagacgagctgaagtgcctggatgctccggtgctg
acccaggctgagtgtaaagcctcctaccctggaaagattaccaacagcatgttctgtgtg
ggcttccttgagggaggcaaggattcctgccagcgtgactctggtggccctgtggtctgc
aacggacagctccaaggagttgtctcctggggccatggctgtgcctggaagaacaggcct
ggagtctacaccaaggtctacaactatgtggactggattaaggacaccatcgctgccaac
agctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (30)   
   RefSeq(nuc) (8)   
   GenBank (11)   
   EMBL (11)   
3D Structure (14)   
   PDB (14)   
Protein domain (2)   
   Pfam (2)   
All databases (85)   

Download RDF
DBGET integrated database retrieval system