1ZZ2: Two Classes of p38alpha MAP Kinase Inhibitors Having a Common Diphenylether Core but Exhibiting Divergent Binding Modes

PDB ID: 1ZZ2Download
MMDB ID: 35563
PDB Deposition Date: 2005/6/13
Updated in MMDB: 2005/11
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 1ZZ2: monomeric; determined by author
Molecular Components in 1ZZ2
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 14
(Gene symbol: MAPK14)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
octyl beta-D-glucopyranosideoctyl beta-D-glucopyranoside
2
1
N-[3-(4-FLUOROPHENOXY)PHENYL]-4-[(2-HYDROXYBENZYL)AMINO]PIPERIDINE-1-SULFONAMIDEN-[3-(4-FLUOROPHENOXY)PHENYL]-4-[(2-HYDROXYBENZYL)AMINO]PIPERIDINE-1-SULFONAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303