3FLI: Discovery of XL335, a Highly Potent, Selective and Orally-Active Agonist of the Farnesoid X Receptor (FXR)

PDB ID: 3FLIDownload
MMDB ID: 78874
PDB Deposition Date: 2008/12/18
Updated in MMDB: 2009/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 3FLI: monomeric; determined by author and by software (PISA)
Molecular Components in 3FLI
Label Count Molecule
Protein (1 molecule)
1
Bile Acid Receptor
(Gene symbol: NR1H4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-methylethyl 3-[(3,4-difluorophenyl)carbonyl]-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate1-methylethyl 3-[(3,4-difluorophenyl)carbonyl]-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303