3N8W: Crystal Structure of R120Q/Native Cyclooxygenase-1 Heterodimer mutant in complex with Flurbiprofen

PDB ID: 3N8WDownload
MMDB ID: 83675
PDB Deposition Date: 2010/5/28
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.75  Å
Source Organism:
Similar Structures:
Biological Unit for 3N8W: dimeric; determined by author and by software (PISA)
Molecular Components in 3N8W
Label Count Molecule
Proteins (2 molecules)
1
Prostaglandin G/H Synthase 1
(Gene symbol: PTGS1)
Molecule annotation
1
Prostaglandin G/H Synthase 1
(Gene symbol: PTGS1)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
8
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
2-acetamido-2-deoxy-alpha-D-glucopyranose2-acetamido-2-deoxy-alpha-D-glucopyranose
3
3
beta-D-mannopyranosebeta-D-mannopyranose
4
3
alpha-D-mannopyranosealpha-D-mannopyranose
5
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
6
1
FLURBIPROFENFLURBIPROFEN
7
3
octyl beta-D-glucopyranosideoctyl beta-D-glucopyranoside
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303