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2PK6:
Crystal Structure of HIV-1 Protease (Q7K, L33I, L63I) in Complex with KNI-10033
PDB ID:
2PK6
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MMDB ID:
46592
PDB Deposition Date:
2007/4/17
Updated in MMDB:
2021/10
Experimental Method:
x-ray diffraction
Resolution:
1.45 Å
Source Organism:
Human immunodeficiency virus 1
Similar Structures:
VAST+
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Biological Unit for 2PK6: dimeric; determined by author and by software (PISA)
Molecular Components in 2PK6
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Protease
(Gene symbol:
gag-pol
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(4R)-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-3-[(2S,3S)-2-hydroxy-3-({N-[(isoquinolin-5-yloxy)acetyl]-S-methyl- L-cysteinyl}amino)-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide
2
1
GLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303