3GFE: Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor

PDB ID: 3GFEDownload
MMDB ID: 75312
PDB Deposition Date: 2009/2/26
Updated in MMDB: 2009/08
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3GFE: monomeric; determined by author and by software (PISA)
Molecular Components in 3GFE
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 14
(Gene symbol: MAPK14)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamideN-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303