3HRF: Crystal structure of Human PDK1 kinase domain in complex with an allosteric activator bound to the PIF-pocket

PDB ID: 3HRFDownload
MMDB ID: 76732
PDB Deposition Date: 2009/6/9
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 3HRF: monomeric; determined by author and by software (PISA)
Molecular Components in 3HRF
Label Count Molecule
Protein (1 molecule)
1
3-phosphoinositide-dependent Protein Kinase 1
(Gene symbol: PDPK1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
2
1
(2Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid(2Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid
3
2
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303