3LCO: Inhibitor Bound to A DFG-Out structure of the Kinase Domain of CSF-1R

PDB ID: 3LCODownload
MMDB ID: 84803
PDB Deposition Date: 2010/1/11
Updated in MMDB: 2010/09
Experimental Method:
x-ray diffraction
Resolution: 3.4  Å
Source Organism:
Similar Structures:
Biological Unit for 3LCO: monomeric; determined by author and by software (PISA)
Molecular Components in 3LCO
Label Count Molecule
Protein (1 molecule)
1
Macrophage Colony-stimulating Factor 1 Receptor
(Gene symbol: CSF1R)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-({4-methoxy-5-[(4-methoxybenzyl)oxy]pyridin-2-yl}methoxy)-5-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-amine3-({4-methoxy-5-[(4-methoxybenzyl)oxy]pyridin-2-yl}methoxy)-5-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303