3MVH: Crystal structure of Akt-1-inhibitor complexes

PDB ID: 3MVHDownload
MMDB ID: 82521
PDB Deposition Date: 2010/5/4
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 2.01  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3MVH: dimeric; determined by author and by software (PISA)
Molecular Components in 3MVH
Label Count Molecule
Proteins (2 molecules)
1
V-akt Murine Thymoma Viral Oncogene Homolog 1 (Akt1)
Molecule annotation
1
Gsk3-beta Peptide
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MANGANESE (II) IONMANGANESE (II) ION
2
1
N-{[(3S)-3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl}-2,4-difluorobenzamideN-{[(3S)-3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl}-2,4-difluorobenzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303