4DUS: Structure Of Bace-1 (beta-secretase) In Complex With N-((2s,3r)-1-(4- Fluorophenyl)-3-hydroxy-4-((6'-neopentyl-3',4'- Dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl)amino) Butan-2-yl)acetamide

PDB ID: 4DUSDownload
MMDB ID: 103777
PDB Deposition Date: 2012/2/22
Updated in MMDB: 2012/10
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 4DUS: monomeric; determined by author and by software (PISA)
Molecular Components in 4DUS
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
7
Iodide IonIodide Ion
2
2
GlycerolGlycerin; Propane-1,2,3-triol
3
1
N-((2s,3r)-1-(4-Fluorophenyl)-3-Hydroxy-4-((6'-Neopentyl-3',4'-Dihydrospiro[cyclobutane-1,2'-Pyrano[2,3-B]pyridin]-4'-Yl)amino)butan-2-Yl)acetamideN-((2s,3r)-1-(4-Fluorophenyl)-3-Hydroxy-4-((6'-Neopentyl-3',4'-Dihydrospiro[cyclobutane-1,2'-Pyrano[2,3-B]pyridin]-4'-Yl)amino)butan-2-Yl)acetamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303