NCBI
National Center for
Biotechnology Information
Search
4E73:
Crystal structure of JNK1beta-JIP in complex with an azaquinolone inhbitor
PDB ID:
4E73
Download
MMDB ID:
110489
PDB Deposition Date:
2012/3/16
Updated in MMDB:
2014/10
Experimental Method:
x-ray diffraction
Resolution:
2.27 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4E73: dimeric; determined by author and by software (PISA)
Molecular Components in 4E73
Label
Count
Molecule
Proteins (2 molecules)
A
1
Mitogen-activated Protein Kinase 8
(Gene symbol:
MAPK8
)
B
1
C-jun-amino-terminal Kinase-interacting Protein 1
(Gene symbol:
MAPK8IP1
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
methyl 3-(4-{[(1R,2S,3S,5S,7s)-5-aminotricyclo[3.3.1.1~3,7~]dec-2-yl]carbamoyl}benzyl)-4-oxo-1-phenyl-1,4-dihydro-1,8-naphthyridine-2-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303