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4I4G:
Crystal structure of CYP3A4 ligated to oxazole-substituted desoxyritonavir
PDB ID:
4I4G
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MMDB ID:
109397
PDB Deposition Date:
2012/11/27
Updated in MMDB:
2023/09
Experimental Method:
x-ray diffraction
Resolution:
2.718 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4I4G: monomeric; determined by author
Molecular Components in 4I4G
Label
Count
Molecule
Protein (1 molecule)
A
1
Cytochrome P450 3A4
(Gene symbol:
CYP3A4
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
PROTOPORPHYRIN IX CONTAINING FE
2
1
N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-N-[(2R,5R)-5-{[(1,3-oxazol-5-ylmethoxy)carbonyl]amino}-1,6-diphenylhexan-2-yl]-L-valinamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303