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3S92:
Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1
PDB ID:
3S92
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MMDB ID:
92033
PDB Deposition Date:
2011/5/31
Updated in MMDB:
2023/09
Experimental Method:
x-ray diffraction
Resolution:
1.36 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3S92: monomeric; determined by author and by software (PISA)
Molecular Components in 3S92
Label
Count
Molecule
Protein (1 molecule)
A
1
Bromodomain-containing Protein 3
(Gene symbol:
BRD3
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
(6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium
2
1
1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303