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12849Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase
11626Crystal Structure of the RNA-dependent RNA Polymerase of Hepatitis C Virus
19189Hepatitis C Virus RNA Polymerase in Complex With GTP and Manganese
19190Hepatitis C Virus RNA Polymerase in Complex With UTP and Manganese
22380Hc-j4 RNA Polymerase Apo-form
22381Hc-j4 RNA Polymerase Complexed With UTP
22382Hc-j4 RNA Polymerase Complexed With Short RNA Template Strand
22402Hepatitis C Virus RNA Polymerase in Complex With Non- Nucleoside Analogue Inhibitor
22403Hepatitis C Virus RNA Polymerase in Complex With Non- Nucleoside Analogue Inhibitor
26788Crystal Structure of HCV Ns5b RNA Polymerase Complexed With a Novel Non-competitive Inhibitor
11637Crystal Structure of the RNA Directed RNA Polymerase of Hepatitis C Virus
32963Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With Inhibitor Pha-00729145
33797Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With Inhibitor Pha-00799585
37096Hepatitis C Virus Ns5b RNA Polymerase in Complex With a Covalent Inhibitor (5h)
37097Hepatitis C Virus Ns5b RNA Polymerase in Complex With a Covalent Inhibitor (5x)
37098Hepatitis C Virus Ns5b RNA Polymerase in Complex With a Covalent Inhibitor (5ee)
34015Crystal Structure of Hepatitis C Virus Polymerase in Complex With an Allosteric Inhibitor (Compound 1)
34016Crystal Structure of Hepatitis C Virus Polymerase in Complex With an Allosteric Inhibitor (Compound 2)
40332X-ray Crystal Structure of Hepatitis C Virus RNA Dependent RNA Polymerase in Complex With Non-nucleoside Analogue Inhibitor
40333X-ray Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase in Complex With Non-nucleoside Analogue Inhibitor
40334X-ray Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase in Complex With Non-nucleoside Inhibitor
43260Crystal Structure of HCV Ns5b RNA Polymerase Complexed With a Tetracyclic Inhibitor
43795Crystal Structure of Ns5b BK Strain (Delta 24) in Complex With a 3-(1, 1-dioxo-2h-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1h)-quinolinone
39957Structure of a Proline Sulfonamide Inhibitor Bound to HCV Ns5b Polymerase
44971Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b With Nni-2 Inhibitor
44972Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b With Nni-1 Inhibitor
41014Crystal Structure of HCV Ns5b RNA Polymerase in Complex With Novel Class of Dihydropyrone-containing Inhibitor
42881HCV Ns5b Allosteric Inhibitor Complex
42882HCV Ns5b Allosteric Inhibitor Complex
42307Novel Thiazolones as HCV Ns5b Polymerase Inhibitors: Further Designs, Synthesis, SAR and X-ray Complex Structure
42965Isothiazoles as Active-site Inhibitors of HCV Ns5b Polymerase
44573Crystal Structure of Hepatitis C Virus Polymerase in Complex With Inhibitor Sb655264
44574Crystal Structure of Hepatitis C Virus Polymerase in Complex With Inhibitor Sb698223
44653Thiazolone-acylsulfonamides as Novel HCV Ns5b Polymerase Allosteric Inhibitors: Convergence of Structure-based Drug Design and X-ray Crystallographic Study
59439Structure of HCV Ns5b Bound to an Anthranilic Acid Inhibitor
59441Structure of HCV Ns5b Bound to an Anthranilic Acid Inhibitor
75995Crystal Structure of Hepatitis C Virus Ns5b Polymerase in Complex With Thienopyrrole-based Finger-loop Inhibitors
75875Crystal Structure of Hepatitis C Virus Ns5b Polymerase From 1B Genotype in Complex With a Non-nucleoside Inhibitor
84955Identification of Novel Allosteric Inhibitors of Hepatitis C Virus Ns5b Polymerase Thumb Domain (Site II) by Structure-based Design
89614Hcv-j4 Ns5b Polymerase Orthorhombic Crystal Form
89615Hcv-j4 Ns5b Polymerase Point Mutant Orthorhombic Crystal Form
89616Hcv-j4 Ns5b Polymerase Trigonal Crystal Form
89617Hcv-h77 Ns5b APO Polymerase
89618Hcv-h77 Ns5b Polymerase Complexed With GTP
87425Structure of Mk-3281, a Potent Non-nucleoside Finger-loop Inhibitor, in Complex With the Hepatitis C Virus Ns5b Polymerase
70648Structure of Hepatitis C Virus Ns5b Polymerase in a NEW Crystal Form
68629Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor
68631Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor
68632Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor
69929Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor
63856Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b in Complex With Small Molecule Fragments
63857Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b in Complex With Small Molecule Fragments
63858Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b in Complex With Optimized Small Molecule Fragments
63859Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b in Complex With Optimized Small Molecule Fragments
63860Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b in Complex With Optimized Small Molecule Fragments
63861Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b in Complex With Optimized Small Molecule Fragments
69530Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor
70811HCV Polymerase in Complex With a 1,5 Benzodiazepine Inhibitor
70976Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor
70977Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor
72735Crystal Structure of HCV Ns5b Polymerase With a Novel Benzisothiazole Inhibitor
72738Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor
76047Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor
69868Hepatitis C Virus Polymerase Ns5b (BK 1-570) With Hcv-796 Inhibitor
69869Hepatitis C Virus Polymerase Ns5b (Con1 1-570) With Hcv-796 Inhibitor
70154Crystal Structure of HCV Ns5b RNA Polymerase in Complex With
76565Hepatitis C Virus Polymerase Ns5b (BK 1-570) With Thiazine Inhibitor
77486HCV Ns5b Polymerase in Complex With 1,5 Benzodiazepine Inhibitor 1B
77487HCV Ns5b Polymerase in Complex With 1,5 Benzodiazepine Inhibitor 4C
73355HCV Ns5b Polymerase in Complex With 1,5 Benzodiazepine Inhibitor (R)- 11D
78548Crystal Structure of HCV Ns5b Polymerase With a Novel Monocyclic Dihydropyridinone Inhibitor
78561Crystal Structure of HCV Ns5b Polymerase in Complex With a Novel Bicyclic Dihydro-pyridinone Inhibitor
76578Hepatitis C Virus Polymerase Ns5b With Thiazine Inhibitor 2
76579Hepatitis C Virus Polymerase Ns5b With Saccharin Inhibitor
76580Hepatitis C Virus Polymerase Ns5b With Saccharin Inhibitor 1
77310Crystal Structure of HCV Ns5b 1B With (1,1-dioxo-2h-[1,2, 4]benzothiadiazin-3-yl) Azolo[1,5-a]pyrimidine Derivative
76587HCV Ns5b Polymerase Complex With a Substituted Benzothiadizine
82310HCV Ns5b Genotype 1A in Complex With 1,5 Benzodiazepine Inhi
82311HCV Ns5b Polymerase Genotype 1B in Complex With 1,5 Benzodiazepine 6
78600Crystal Structure of HCV Ns5b Polymerase With a Novel Monocyclic Dihydro-pyridinone Inhibitor
80991Inhibitors of Hepatitis C Virus Polymerase: Synthesis and Characterization of Novel 6-fluoro-n-[2-hydroxy-1(s)-benzam
83649Hepatitis C Virus Polymerase Ns5b (Bk) With Amide Bioisostere Thumb Site Inhibitor
85780Crystal Structure of HCV Ns5b Polymerase
85781Crystal Structure of HCV Ns5b Polymerase
86360HCV Ns5b With a Bound Quinolone Inhibitor
90174Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With (2e)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7- Dihydro-5h-indolo[1,2-d][1,4]benzodiazepin-10-yl) Carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic Acid
90032Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With (2e)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7- Dihydro-5h-indolo[1,2-d][1,4]benzodiazepin-10-yl) Carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic Acid and (2r)-4-(2,6-dimethoxypyrimidin-4-yl)-1-[(4-ethylphenyl)sulfonyl]- N-(4-methoxybenzyl)piperazine-2-carboxamide
90033Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With (2e)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7- Dihydro-5h-indolo[1,2-d][1,4]benzodiazepin-10-yl) Carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic Acid and (2r)-4-(2,6-dimethoxypyrimidin-4-yl)-n-(4-methoxybenzyl)-1-{[4- (Trifluoromethoxy)phenyl]sulfonyl}piperazine-2-carboxamide
90034Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With (2e)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7- Dihydro-5h-indolo[1,2-d][1,4]benzodiazepin-10-yl) Carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic Acid and (2r)-4-(6-chloropyridazin-3-yl)-n-(4-methoxybenzyl)-1-{[4- (Trifluoromethoxy)phenyl]sulfonyl}piperazine-2-carboxamide
90035Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With (2e)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7- Dihydro-5h-indolo[1,2-d][1,4]benzodiazepin-10-yl) Carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic Acid and N-cyclopropyl-6-[(3r)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}- 4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3- Carboxamide
90036Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Genotype 1A Complex With N-cyclopropyl-6-[(3r)-3-{[4- (Trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy) Phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide
90037Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Genotype 1A Complex With N-[(2s)-butan-2-yl]-6-[(3r)-3- {[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy) Phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide