Toward the development of innovative bifunctional agents to induce differentiation and to promote apoptosis in leukemia: clinical candidates and perspectives

J Med Chem. 2010 Oct 14;53(19):6779-810. doi: 10.1021/jm100189a.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents* / chemistry
  • Antineoplastic Agents* / pharmacology
  • Antineoplastic Agents* / therapeutic use
  • Apoptosis / drug effects*
  • Cell Differentiation / drug effects
  • Clinical Trials as Topic
  • Drug Evaluation, Preclinical
  • Drug Resistance, Multiple
  • Drug Resistance, Neoplasm
  • Humans
  • Leukemia / drug therapy*
  • Leukemia / genetics
  • Leukemia / pathology
  • Multipotent Stem Cells / pathology
  • Neoplastic Stem Cells / drug effects
  • Neoplastic Stem Cells / pathology
  • Pharmacogenetics

Substances

  • Antineoplastic Agents