Your request to link to rcsb for Aurora kinase A

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• 1MQ4: crystal structure of aurora-a protein kinase (10.1016/S0969-2126(02)00907-3 )
• 1MUO: crystal structure of aurora-2, an oncogenic serine- threonine kinase (10.1074/JBC.C200426200 )
• 1OL5: structure of aurora-a 122-403, phosphorylated on thr287, thr288 and bound to tpx2 1-43 (10.1016/S1097-2765(03)00392-7 )
• 1OL6: structure of unphosphorylated d274n mutant of aurora-a (10.1016/S1097-2765(03)00392-7 )
• 1OL7: structure of human aurora-a 122-403 phosphorylated on thr287, thr288 (10.1016/S1097-2765(03)00392-7 )
• 2BMC: aurora-2 t287d t288d complexed with pha-680632 (10.1021/JM049076M )
• 2C6D: aurora a kinase activated mutant (t287d) in complex with adpnp (10.1016/J.BMCL.2005.11.053 )
• 2C6E: aurora a kinase activated mutant (t287d) in complex with a 5-aminopyrimidinyl quinazoline inhibitor (10.1016/J.BMCL.2005.11.053 )
• 2DWB: aurora-a kinase complexed with amppnp
• 2J4Z: structure of aurora-2 in complex with pha-680626 (10.1021/JM060897W )
• 2J50: structure of aurora-2 in complex with pha-739358 (10.1021/JM060897W )
• 2NP8: structural basis for the inhibition of aurora a kinase by a novel class of high affinity disubstituted pyrimidine inhibitors (10.1016/J.BMCL.2006.10.086 )
• 2W1C: structure determination of aurora kinase in complex with inhibitor (10.1021/JM800984V )
• 2W1D: structure determination of aurora kinase in complex with inhibitor (10.1021/JM800984V )
• 2W1E: structure determination of aurora kinase in complex with inhibitor (10.1021/JM800984V )
• 2W1F: structure determination of aurora kinase in complex with inhibitor (10.1021/JM800984V )
• 2W1G: structure determination of aurora kinase in complex with inhibitor (10.1021/JM800984V )
• 2WQE: structure of s155r aurora-a somatic mutant (10.1074/JBC.M109.032722 )
• 2WTV: aurora-a inhibitor structure (10.1042/BJ20091530 )
• 2WTW: aurora-a inhibitor structure (2nd crystal form) (10.1042/BJ20091530 )
• 2X6D: aurora-a bound to an inhibitor (10.1021/JM100262J )
• 2X6E: aurora-a bound to an inhibitor (10.1021/JM100262J )
• 2X81: structure of aurora a in complex with mln8054 (10.1021/CB100053Q )
• 2XNE: structure of aurora-a bound to an imidazopyrazine inhibitor (10.1016/J.BMCL.2010.08.091 )
• 2XNG: structure of aurora-a bound to a selective imidazopyrazine inhibitor (10.1016/J.BMCL.2010.08.091 )
• 2XRU: aurora-a t288e complexed with pha-828300 (10.1016/J.BMC.2010.07.048 )
• 3COH: crystal structure of aurora-a in complex with a pentacyclic inhibitor (10.1021/JM800052B )
• 3D14: crystal structure of mouse aurora a (asn186->gly, lys240->arg, met302- >leu) in complex with 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)- ethyl]- thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea (10.1016/J.BMCL.2008.07.073 )
• 3D15: crystal structure of mouse aurora a (asn186->gly, lys240->arg, met302- >leu) in complex with 1-(3-chloro-phenyl)-3-{5-[2-(thieno[3,2- d]pyrimidin-4-ylamino)- ethyl]-thiazol-2-yl}-urea [sns-314] (10.1016/J.BMCL.2008.07.073 )
• 3D2I: crystal structure of mouse aurora a (asn186->gly, lys240- >arg, met302->leu) in complex with 1-{5-[2-(1-methyl-1h- pyrazolo[4,3-d]pyrimidin-7-ylamino)-ethyl]-thiazol-2-yl}-3- (3-trifluoromethyl-phenyl)-urea
• 3D2K: crystal structure of mouse aurora a (asn186->gly, lys240- >arg, met302->leu) in complex with [7-(2-{2-[3-(3-chloro- phenyl)-ureido]-thiazol-5-yl}-ethylamino)-pyrazolo[4,3- d]pyrimidin-1-yl]-acetic acid
• 3DAJ: crystal structure of aurora a complexed with an inhibitor discovered through site-directed dynamic tethering (10.1016/J.BMCL.2008.06.011 )
• 3DJ5: crystal structure of the mouse aurora-a catalytic domain (asn186->gly, lys240->arg, met302->leu) in complex with compound 290.
• 3DJ6: crystal structure of the mouse aurora-a catalytic domain (asn186->gly, lys240->arg, met302->leu) in complex with compound 823.
• 3DJ7: crystal structure of the mouse aurora-a catalytic domain (asn186->gly, lys240->arg, met302->leu) in complex with compound 130.
• 3E5A: crystal structure of aurora a in complex with vx-680 and tpx2 (10.1110/PS.036590.108 )
• 3EFW: structure of auroraa with pyridyl-pyrimidine urea inhibitor (10.1016/J.BMCL.2008.11.056 )
• 3FDN: structure-based drug design of novel aurora kinase a inhibitors: structure basis for potency and specificity (10.1021/JM801270E )
• 3H0Y: aurora a in complex with a bisanilinopyrimidine (10.1021/JM9000314 )
• 3H0Z: aurora a in complex with a bisanilinopyrimidine (10.1021/JM9000314 )
• 3H10: aurora a inhibitor complex (10.1021/JM9000314 )
• 3HA6: crystal structure of aurora a in complex with tpx2 and compound 10 (10.1038/NCHEMBIO.211 )
• 3K5U: identification, sar studies and x-ray cocrystal analysis of a novel furano-pyrimidine aurora kinase a inhibitor (10.1002/CMDC.200900339 )
• 3LAU: crystal structure of aurora2 kinase in complex with a gsk3beta inhibitor (10.1016/J.BMCL.2010.01.114 )
• 3M11: crystal structure of aurora a kinase complexed with inhibitor (10.1021/JM1000198 )
• 3MYG: aurora a kinase complexed with sch 1473759 (10.1021/ML100063W )
• 3NRM: imidazo[1,2-a]pyrazine-based aurora kinase inhibitors (10.1016/J.BMCL.2010.07.008 )
• 3O50: crystal structure of benzamide 9 bound to auroraa (10.1021/JM100394Y )
• 3O51: crystal structure of anthranilamide 10 bound to auroraa (10.1021/JM100394Y )
• 3P9J: aurora a kinase domain with phthalazinone pyrazole inhibitor (10.1021/JM101346R )
• 3QBN: structure of human aurora a in complex with a diaminopyrimidine (10.1021/CB200112Y )
• 3R21: design, synthesis, and biological evaluation of pyrazolopyridine- sulfonamides as potent multiple-mitotic kinase (mmk) inhibitors (part i) (10.1016/J.BMCL.2011.06.129 )
• 3R22: design, synthesis, and biological evaluation of pyrazolopyridine- sulfonamides as potent multiple-mitotic kinase (mmk) inhibitors (part i) (10.1016/J.BMCL.2011.06.129 )
• 3UNZ: aurora a in complex with rpm1679 (10.1021/CB200508B )
• 3UO4: aurora a in complex with rpm1680 (10.1021/CB200508B )
• 3UO5: aurora a in complex with yl1-038-31 (10.1021/CB200508B )
• 3UO6: aurora a in complex with yl5-083 (10.1021/CB200508B )
• 3UOD: aurora a in complex with rpm1693 (10.1021/CB200508B )
• 3UOH: aurora a in complex with rpm1722 (10.1021/CB200508B )
• 3UOJ: aurora a in complex with rpm1715 (10.1021/CB200508B )
• 3UOK: aurora a in complex with yl5-81-1 (10.1021/CB200508B )
• 3UOL: aurora a in complex with so2-162 (10.1021/CB200508B )
• 3UP2: aurora a in complex with rpm1686 (10.1021/CB200508B )
• 3UP7: aurora a in complex with yl1-038-09 (10.1021/JM300334D )
• 3VAP: synthesis and sar studies of imidazo-[1,2-a]-pyrazine aurora kinase inhibitors with improved off target kinase selectivity (10.1016/J.BMCL.2012.03.051 )
• 3W10: aurora kinase a complexed to pyrazole aminoquinoline i
• 3W16: structure of aurora kinase a complexed to pyrazole-aminoquinoline inhibitor iii
• 3W18: structure of aurora kinase a complexed to benzoimidazole-indazole inhibitor xiii
• 3W2C: structure of aurora kinase a complexed to benzoimidazole-indazole inhibitor xv
• 4B0G: complex of aurora-a bound to an imidazopyridine-based inhibitor (10.1021/JM300952S )
• 4BN1: crystal structure of v174m mutant of aurora-a kinase (10.1021/CB400425T )
• 4BYI: aurora a kinase bound to a highly selective imidazopyridine inhibitor (10.1021/JM401115G )
• 4BYJ: aurora a kinase bound to a highly selective imidazopyridine inhibitor (10.1021/JM401115G )
• 4C3P: structure of dephosphorylated aurora a (122-403) bound to tpx2 and amppcp (10.7554/ELIFE.02667 )
• 4C3R: structure of dephosphorylated aurora a (122-403) bound to amppcp (10.7554/ELIFE.02667 )
• 4CEG: crystal structure of aurora a 122-403 c290a, c393a bound to adp (10.1107/S2053230X15002290 )
• 4DEA: aurora a in complex with yl1-038-18 (10.1021/JM300334D )
• 4DEB: aurora a in complex with rk2-17-01 (10.1021/JM300334D )
• 4DED: aurora a in complex with yl1-038-21 (10.1021/JM300334D )
• 4DEE: aurora a in complex with adp (10.1021/JM300334D )
• 4DHF: structure of aurora a mutant bound to biogenidec cpd 15 (10.1016/J.BMCL.2012.04.085 )
• 4J8M: aurora a in complex with cd532 (10.1016/J.CCR.2014.07.015 )
• 4J8N: aurora a kinase apo (10.1016/J.CCR.2014.07.015 )
• 4JAI: crystal structure of aurora kinase a in complex with n-{4-[(6-oxo-5,6- dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide (10.1016/J.BMCL.2013.03.008 )
• 4JAJ: crystal structure of aurora kinase a in complex with benzo[c][1, 8]naphthyridin-6(5h)-one (10.1016/J.BMCL.2013.03.008 )
• 4JBO: novel aurora kinase inhibitors reveal mechanisms of hurp in nucleation of centrosomal and kinetochore microtubules (10.1073/PNAS.1220523110 )
• 4JBP: novel aurora kinase inhibitors reveal mechanisms of hurp in nucleation of centrosomal and kinetochore microtubules (10.1073/PNAS.1220523110 )
• 4JBQ: novel aurora kinase inhibitors reveal mechanisms of hurp in nucleation of centrosomal and kinetochore microtubules (10.1073/PNAS.1220523110 )
• 4O0S: crystal structures of human kinase aurora a
• 4O0U: crystal structures of human kinase aurora a
• 4O0W: crystal structures of human kinase aurora a
• 4PRJ: aurora a kinase domain with compound 2 (n-[1-(3-cyanobenzyl)-1h- pyrazol-4-yl]-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide) (10.1021/JM500550E )
• 4UYN: sar156497 an exquisitely selective inhibitor of aurora kinases (10.1021/JM501326K )
• 4UZD: sar156497 an exquisitely selective inhibitor of aurora kinases (10.1021/JM501326K )
• 4UZH: sar156497 an exquisitely selective inhibitor of aurora kinases (10.1021/JM501326K )
• 4ZS0: human aurora a catalytic domain bound to sb-6-oh (10.1021/ACS.JMEDCHEM.6B00709 )
• 4ZTQ: human aurora a catalytic domain bound to fk932 (10.1021/ACS.JMEDCHEM.6B00709 )
• 4ZTR: human aurora a catalytic domain bound to fk1141 (10.1021/ACS.JMEDCHEM.6B00709 )
• 4ZTS: human aurora a catalytic domain bound to fk1142 (10.1021/ACS.JMEDCHEM.6B00709 )
• 5AAD: aurora a kinase bound to an imidazopyridine inhibitor (7a) (10.1016/J.BMCL.2015.08.003 )
• 5AAE: aurora a kinase bound to an imidazopyridine inhibitor (14d) (10.1016/J.BMCL.2015.08.003 )
• 5AAF: aurora a kinase bound to an imidazopyridine inhibitor (14a) (10.1016/J.BMCL.2015.08.003 )
• 5AAG: aurora a kinase bound to an imidazopyridine inhibitor (14b) (10.1016/J.BMCL.2015.08.003 )
• 5DN3: aurora a in complex with atp and aa35. (10.1038/SREP28528 )
• 5DNR: aurora a kinase in complex with atp in space group p41212 (10.1038/SREP28528 )
• 5DOS: aurora a kinase in complex with aa35 and atp in space group p6122 (10.1038/SREP28528 )
• 5DPV: aurora a kinase in complex with aa35 and jnj-7706621 in space group p6122 (10.1038/SREP28528 )
• 5DR2: aurora a kinase in complex with aa30 and atp in space group p6122 (10.1038/SREP28528 )
• 5DR6: aurora a kinase in complex with aa30 and jnj-7706621 in space group p6122 (10.1038/SREP28528 )
• 5DR9: aurora a kinase in complex with aa29 and jnj-7706621 in space group p6122 (10.1038/SREP28528 )
• 5DRD: aurora a kinase in complex with atp in space group p6122 (10.1038/SREP28528 )
• 5DT0: aurora a kinase in complex with jnj-7706621 in space group p6122 (10.1038/SREP28528 )
• 5DT3: aurora a kinase in complex with atp in space group p6122 (10.1038/SREP28528 )
• 5DT4: aurora a kinase in complex with aa35 and atp in space group p6122 (10.1038/SREP28528 )
• 5EW9: crystal structure of aurora a kinase domain bound to mk-5108 (10.3389/FONC.2015.00285 )
• 5G15: structure aurora a (122-403) bound to activating monobody mb1 and amppcp (10.1073/PNAS.1906024116 )
• 5G1X: crystal structure of aurora-a kinase in complex with n-myc 23-nov-16 5g1x 1 title (10.1073/PNAS.1610626113 )
• 5L8J: aurora-a kinase domain in complex with vnar-d01 s93r (10.1098/RSOB.160089 )
• 5L8K: aurora-a kinase domain in complex with vnar-d01 (crystal form 2) (10.1098/RSOB.160089 )
• 5L8L: aurora-a kinase domain in complex with vnar-d01 (crystal form 1) (10.1098/RSOB.160089 )
• 5LXM: crystal structure of aurora-a bound to a hydrocarbon-stapled proteomimetic of tpx2 (10.1021/ACSCHEMBIO.6B00727 )
• 5OBJ: aurora a kinase in complex with 2-(3-fluorophenyl)quinoline-4- carboxylic acid and atp (10.1039/C7CC05379G )
• 5OBR: aurora a kinase in complex with 2-(3-chloro-5-fluorophenyl)quinoline- 4-carboxylic acid and jnj-7706621 (10.1039/C7CC05379G )
• 5ODT: aurora-a in complex with tacc3 (10.15252/EMBJ.201797902 )
• 5ONE: crystal structure of aurora-a in complex with fmf-03-145-1 (compound 2) (10.1016/J.BMCL.2017.08.016 )
• 5ORL: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5ORN: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5ORO: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5ORP: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5ORR: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5ORS: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5ORT: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5ORV: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5ORW: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5ORX: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5ORY: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5ORZ: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5OS0: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5OS1: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5OS2: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5OS3: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5OS4: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5OS5: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5OS6: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5OSD: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5OSE: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5OSF: crystal structure of aurora-a kinase in complex with an allosterically binding fragment (10.1021/ACSCHEMBIO.7B00537 )
• 5ZAN: crystal structure of aurora-a in complex with a new quinazoline inhibitor
• 6C2R: aurora a ligand complex (10.1158/2159-8290.CD-18-0469 )
• 6C2T: aurora a ligand complex (10.1158/2159-8290.CD-18-0469 )
• 6C83: structure of aurora a (122-403) bound to inhibitory monobody mb2 and amppcp (10.1073/PNAS.1906024116 )
• 6CPE: structure of apo, dephosphorylated aurora a (122-403) in an active conformation (10.7554/ELIFE.36656 )
• 6CPF: structure of dephosphorylated aurora a (122-403) bound to amppcp in an active conformation (10.7554/ELIFE.36656 )
• 6CPG: structure of dephosphorylated aurora a (122-403) in complex with inhibiting monobody and at9283 in an inactive conformation (10.7554/ELIFE.36656 )
• 6GRA: human aurka bound to brd-7880
• 6HJJ: crystal structure of aurora-a l210c catalytic domain in complex with asdo6 ligand (10.1021/ACSCHEMBIO.8B00592 )
• 6HJK: crystal structure of aurora-a l210c catalytic domain in complex with asdo2 (10.1021/ACSCHEMBIO.8B00592 )
• 6I2U: aurora-a kinase domain in complex with coenzyme a (10.1016/J.REDOX.2019.101318 )
• 6R49: aurora-a in complex with shape-diverse fragment 39 (10.1002/CHEM.201900815 )
• 6R4A: aurora-a in complex with shape-diverse fragment 55 (10.1002/CHEM.201900815 )
• 6R4B: aurora-a in complex with shape-diverse fragment 56 (10.1002/CHEM.201900815 )
• 6R4C: aurora-a in complex with shape-diverse fragment 57 (10.1002/CHEM.201900815 )
• 6R4D: aurora-a in complex with shape-diverse fragment 58 (10.1002/CHEM.201900815 )
• 6VPG: tpx2 residues 7-20 fused to aurora a residues 116-389 in complex with amp-pnp (10.1126/SCISIGNAL.ABB6707 )
• 6VPH: tpx2 residues 7-20 fused to aurora a residues 116-389 modified with cacodylate and in complex with amp-pnp (10.1126/SCISIGNAL.ABB6707 )
• 6VPI: tpx2 residues 7-20 fused to aurora a residues 116-389 c247v + d256n + c319v triple mutant disulfide homodimer in complex with amp-pnp (10.1126/SCISIGNAL.ABB6707 )
• 6VPJ: tpx2 residues 7-20 fused to aurora a residues 116-389 c247v + c319v double mutant dephosphorylated, and in complex with amp-pnp (10.1126/SCISIGNAL.ABB6707 )
• 6VPL: tpx2 residues 7-20 fused to aurora a residues 116-389 with c290 disulfide bonded to compound 7-80, and in complex with amp-pnp (10.1126/SCISIGNAL.ABB6707 )
• 6VPM: tpx2 residues 7-20 fused to aurora a residues 116-389 with c290 disulfide bonded to compound 8-34, and in complex with amp-pnp (10.1126/SCISIGNAL.ABB6707 )
• 6XKA: tpx2 residues 7-20 fused to aurora a residues 116-389 dephosphorylated, and coalated on c290 (10.1126/SCISIGNAL.ABB6707 )
• 6Z4Y: crystal structure of aurora a (stk6) in complex with macrocycle ods2003208
• 7AYH: crystal structure of aurora a in complex with 7-(2-anilinopyrimidin-4- yl)-1-benzazepin-2-one derivative (compound 2c) (10.3390/MOLECULES26061611 )
• 7AYI: crystal structure of aurora a in complex with 7-(2-anilinopyrimidin-4- yl)-1-benzazepin-2-one derivative (compound 2a) (10.3390/MOLECULES26061611 )
• 7O2V: aurora kinase a in complex with the aur-a/pdk1 inhibitor vi8 (10.1016/J.EJMECH.2021.113895 )