Your request to link to rcsb for HIV-1 protease

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• 4DQB: crystal structure of wild-type hiv-1 protease in complex with drv (10.1021/JA2095766 )
• 4DQC: crystal structure of (g16c/l38c) hiv-1 protease in complex with drv (10.1021/JA2095766 )
• 4DQE: crystal structure of (g16c/l38c) hiv-1 protease in complex with drv (10.1021/JA2095766 )
• 5KAO: crystal structure of wild type hiv-1 protease in complex with grl- 10413 (10.1128/AAC.01428-16 )
• 5T84: hiv-1 protease, unbound subtype b l63p construct
• 5T8H: joint x-ray/neutron structure of hiv-1 protease triple mutant (v32i, i47v,v82i) with amprenavir at ph 6.0 (10.1021/ACS.JMEDCHEM.6B01767 )
• 5TYR: x-ray crystal structure of wild type hiv-1 protease in complex with grl-121 (10.7554/ELIFE.28020 )
• 5TYS: x-ray crystal structure of wild type hiv-1 protease in complex with grl-142 (10.7554/ELIFE.28020 )
• 5VCK: hiv protease (pr) with tl-3 in the active site and (z)-n-(thiazol-2- yl)-n'-tosylcarbamimidate in the exosite
• 5VEA: hiv protease (pr) with tl-3 in active site and 4-methylbenzene-1,2- diamine in exosite
• 5W5W: hiv protease (pr) in open form with mg2+ in active site and hive-9 in eye site
• 6B36: crystal structure of hiv protease complexed with (s)-n-(3-fluoro-2-(2- (1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4- fluorophenyl)propanamide (10.1021/ACSMEDCHEMLETT.7B00386 )
• 6B38: crystal structure of hiv protease complexed with n-(3-fluoro-2-(2- ((2s,6r)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3- bis(4-fluorophenyl)propanamide (10.1021/ACSMEDCHEMLETT.7B00386 )
• 6B3C: crystal structure of hiv protease complexed with n-(3-fluoro-2-(2- ((2s,6r)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3- bis(4-fluorophenyl)propanamide (10.1021/ACSMEDCHEMLETT.7B00386 )
• 6B3F: crystal structure of hiv protease complexed with n-(3-fluoro-2-(2- ((2s,5s)-5-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3- bis(4-fluorophenyl)propanamide (10.1021/ACSMEDCHEMLETT.7B00386 )
• 6B3G: crystal structure of hiv protease complexed with n-(3-fluoro-2-(2- ((2s,6s)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3- bis(4-fluorophenyl)propanamide (10.1021/ACSMEDCHEMLETT.7B00386 )
• 6B3H: crystal structure of hiv protease complexed with n-(2-(2-((6r,9s)-2,2- dioxido-2-thia-1,7-diazabicyclo[4.3.1]decan-9-yl)ethyl)-3- fluorophenyl)-3,3-bis(4-fluorophenyl)propanamide (10.1021/ACSMEDCHEMLETT.7B00386 )
• 6B4N: a hydroxymethyl functionality at the 4-position of the 2-phenyloxazole moiety of hiv-1 protease inhibitors involving the p2' ligands (10.1002/CMDC.201700614 )
• 6C8X: wild-type hiv-1 protease in complex with a phenylboronic acid (p2') analog of darunavir (10.1021/JACS.8B07366 )
• 6C8Y: d30n hiv-1 protease in complex with a phenylboronic acid (p2') analog of darunavir (10.1021/JACS.8B07366 )
• 6CDJ: hiv-1 wild type protease with grl-03314a, 6-5-5-ring fused umbrella- like tetrahydropyranofuran as the p2-ligand, a cyclopropylaminobenzothiazole as the p2'-ligand and 3,5- difluorophenylmethyl as the p1-ligand (10.1021/ACS.JMEDCHEM.8B00298 )
• 6CDL: hiv-1 wild type protease with grl-03214a, 6-5-5-ring fused umbrella- like tetrahydropyranofuran as the p2-ligand, a cyclopropylaminobenzothiazole as the p2'-ligand and 3,5- difluorophenylmethyl as the p1-ligand (10.1021/ACS.JMEDCHEM.8B00298 )
• 6DGX: crystal structure of hiv-1 protease nl4-3 wt in complex with darunavir (10.1021/ACSINFECDIS.8B00336 )
• 6DGY: crystal structure of hiv-1 protease nl4-3 wt in complex with umass1 (10.1021/ACSINFECDIS.8B00336 )
• 6DGZ: crystal structure of hiv-1 protease nl4-3 wt in complex with umass6 (10.1021/ACSINFECDIS.8B00336 )
• 6DH0: crystal structure of hiv-1 protease nl4-3 i84v mutant in complex with darunavir (10.1021/ACSINFECDIS.8B00336 )
• 6DH1: crystal structure of hiv-1 protease nl4-3 i84v mutant in complex with umass1 (10.1021/ACSINFECDIS.8B00336 )
• 6DH2: crystal structure of hiv-1 protease nl4-3 i84v mutant in complex with umass6 (10.1021/ACSINFECDIS.8B00336 )
• 6DH3: crystal structure of hiv-1 protease nl4-3 v82i mutant in complex with darunavir (10.1021/ACSINFECDIS.8B00336 )
• 6DH4: crystal structure of hiv-1 protease nl4-3 v82i mutant in complex with umass1 (10.1021/ACSINFECDIS.8B00336 )
• 6DH5: crystal structure of hiv-1 protease nl4-3 v82i mutant in complex with umass6 (10.1021/ACSINFECDIS.8B00336 )
• 6DH6: crystal structure of hiv-1 protease nl4-3 i50v mutant in complex with darunavir (10.1021/ACSINFECDIS.8B00336 )
• 6DH7: crystal structure of hiv-1 protease nl4-3 i50v mutant in complex with umass1 (10.1021/ACSINFECDIS.8B00336 )
• 6DH8: crystal structure of hiv-1 protease nl4-3 i50v mutant in complex with umass6 (10.1021/ACSINFECDIS.8B00336 )
• 6DIF: wild-type hiv-1 protease in complex with tipranavir (10.1021/ACSOMEGA.8B01683 )
• 6DIL: hiv-1 protease with single mutation l76v in complex with tipranavir (10.1021/ACSOMEGA.8B01683 )
• 6DJ1: wild-type hiv-1 protease in complex with lopinavir (10.1021/ACSOMEGA.8B01683 )
• 6DJ2: hiv-1 protease with single mutation l76v in complex with lopinavir (10.1021/ACSOMEGA.8B01683 )
• 6DJ5: hiv-1 protease with mutation l76v in complex with grl-0519 (tris- tetrahydrofuran as p2 ligand) (10.1021/ACSOMEGA.8B01683 )
• 6DJ7: hiv-1 protease with mutation l76v in complex with grl-5010 (gem- difluoro-bis-tetrahydrofuran as p2 ligand) (10.1021/ACSOMEGA.8B01683 )
• 6I45: crystal structure of i13v/i62v/v77i south african hiv-1 subtype c protease containing a d25a mutation
• 6KMP: 100k x-ray structure of hiv-1 protease triple mutant (v32i,i47v,v82i) with tetrahedral intermediate mimic kvs-1 (10.1021/ACSOMEGA.0C00835 )
• 6MCR: x-ray crystal structure of wild type hiv-1 protease in complex with grl-001 (10.1128/AAC.02635-18 )
• 6MCS: x-ray crystal structure of wild type hiv-1 protease in complex with grl-003 (10.1128/AAC.02635-18 )
• 6O48: wild-type hiv-1 protease in complex with a substrate analog ca-p2 (10.1021/ACSOMEGA.9B00683 )
• 6OGP: x-ray crystal structure of wild type hiv-1 protease in complex with grl-063 (10.1038/S41598-020-65993-Z )
• 6OOS: hiv-1 protease nl4-3 l90m mutant in complex with darunavir (10.1021/ACS.BIOCHEM.9B00446 )
• 6OOT: hiv-1 protease nl4-3 l89v, l90m mutant in complex with darunavir (10.1021/ACS.BIOCHEM.9B00446 )
• 6OOU: crystal structure of hiv-1 protease nl4-3 l89v mutant in complex with darunavir (10.1021/ACS.BIOCHEM.9B00446 )
• 6OPS: hiv-1 protease nl4-3 wt in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 6OPT: hiv-1 protease nl4-3 v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 6OPU: hiv-1 protease nl4-3 k45i, m46i, v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 6OPV: hiv-1 protease nl4-3 i13v, g16e, v32i, l33f, k45i, m46i, v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 6OPW: hiv-1 protease nl4-3 i13v, g16e, v32i, l33f, k45i, m46i, a71v, v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 6OPX: hiv-1 protease nl4-3 i13v, g16e, v32i, l33f, k45i, m46i, l76v, v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 6OPY: hiv-1 protease nl4-3 i13v, g16e, v32i, l33f, k45i, m46i, a71v, l76v, v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 6OPZ: hiv-1 protease nl4-3 i13v, g16e, v32i, l33f, k45i, m46i, i54l, a71v, l76v, v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 6OTG: hiv-1 protease triple mutants v32i, i47v, v82i with grl-011-11a (a methylamine bis-tetrahydrofuran p2-ligand, sulfonamide isostere derivate) (10.1016/J.BBRC.2019.05.064 )
• 6OXO: hiv-1 protease nl4-3 wt in complex with lr2-91 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OXP: hiv-1 protease nl4-3 wt in complex with umass3 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OXQ: hiv-1 protease nl4-3 wt in complex with umass8 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OXR: hiv-1 protease nl4-3 wt in complex with lr-82 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OXS: hiv-1 protease nl4-3 wt in complex with lr-76 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OXT: hiv-1 protease nl4-3 wt in complex with lr-84 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OXU: hiv-1 protease nl4-3 wt in complex with lr-99 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OXV: hiv-1 protease nl4-3 wt in complex with lr-85 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OXW: hiv-1 protease nl4-3 wt in complex with lr-100 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OXX: hiv-1 protease nl4-3 wt in complex with lr2-18 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OXY: hiv-1 protease nl4-3 wt in complex with lr2-19 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OXZ: hiv-1 protease nl4-3 wt in complex with lr2-20 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OY0: hiv-1 protease nl4-3 wt in complex with lr2-21 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OY1: hiv-1 protease nl4-3 wt in complex with lr2-26 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OY2: hiv-1 protease nl4-3 wt in complex with lr2-25 (10.1021/ACS.JMEDCHEM.9B00838 )
• 6OYD: x-ray crystal structure of wild type hiv-1 protease in complex with grl-004 (10.1038/S41598-020-65993-Z )
• 6OYR: x-ray crystal structure of wild type hiv-1 protease in complex with grl-002 (10.1038/S41598-020-65993-Z )
• 6PJB: hiv-1 protease nl4-3 wt in complex with lopinavir (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PJC: hiv-1 protease nl4-3 wt in complex with lr4-41 (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PJD: hiv-1 protease nl4-3 wt in complex with lr2-32 (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PJE: hiv-1 protease nl4-3 wt in complex with lr2-43 (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PJF: hiv-1 protease nl4-3 wt in complex with lr2-44 (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PJG: hiv-1 protease nl4-3 wt in complex with lr3-97 (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PJH: hiv-1 protease nl4-3 wt in complex with lr3-28 (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PJI: hiv-1 protease nl4-3 wt in complex with lr3-43 (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PJK: hiv-1 protease nl4-3 wt in complex with lr3-29 (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PJL: hiv-1 protease nl4-3 wt in complex with lr3-95 (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PJM: hiv-1 protease nl4-3 wt in complex with lr2-35 (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PJN: hiv-1 protease nl4-3 wt in complex with lr2-41 (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PJO: hiv-1 protease nl4-3 wt in complex with lr2-42 (10.1021/ACS.JMEDCHEM.0C00529 )
• 6PTP: joint x-ray/neutron structure of hiv-1 protease triple mutant (v32i, i47v,v82i) with tetrahedral intermediate mimic kvs-1 (10.1021/ACSOMEGA.0C00835 )
• 6PU8: room temperature x-ray structure of hiv-1 protease triple mutant (v32i,i47v,v82i) with tetrahedral intermediate of keto-darunavir (10.1021/ACSOMEGA.0C00835 )
• 6U7O: hiv-1 wild type protease with grl-00819a, with phenyl-boronic-acid as p2'-ligand and with a 6-5-5-ring fused crown-like tetrahydropyranofuran as the p2-ligand (10.1002/CMDC.201900508 )
• 6U7P: hiv-1 wild type protease with grl-03119a, with phenyl-boronic-acid as p2'-ligand and with a hexahydro-4h-furo-pyran as the p2-ligand (10.1002/CMDC.201900508 )
• 6UWB: x-ray crystal structure of wild type hiv-1 protease in complex with grl-08513
• 6UWC: x-ray crystal structure of wild type hiv-1 protease in complex with grl-08613
• 6VCE: hiv-1 wild type protease with grl-026-18a, a crown-like tetrahydropyranotetrahydrofuran with a bridged methylene group as a p2 ligand (10.1021/ACSMEDCHEMLETT.9B00670 )
• 6VOD: hiv-1 wild type protease with grl-052-16a, a tricyclic cyclohexane fused tetrahydrofuranofuran (chf-thf) derivative as the p2 ligand (10.1021/ACS.JMEDCHEM.0C00202 )
• 6VOE: hiv-1 wild type protease with grl-019-17a, a tricyclic cyclohexane fused tetrahydrofuranofuran (chf-thf) derivative as the p2 ligand and a aminobenzothiazole(abt)-based p2'-ligand (10.1021/ACS.JMEDCHEM.0C00202 )
• 6W6T: wt hiv-1 protease in complex with phosphonated umass6 (pu6)
• 7DOZ: hiv-1 protease d30n mutant in complex with nelfinavir (10.1080/07391102.2021.1982007 )
• 7DPQ: hiv-1 protease d30n mutant (10.1080/07391102.2021.1982007 )
• 7DT9: d30n hiv protease in complex with saquinavir
• 7HVP: x-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor (10.1073/PNAS.87.22.8805 )
• 7LE3: hiv-1 protease wt (nl4-3) in complex with umass5
• 7LE4: hiv-1 protease wt (nl4-3) in complex with umass7
• 7LE5: hiv-1 protease wt (nl4-3) in complex with umass9
• 7LE6: hiv-1 protease wt (nl4-3) in complex with umass10
• 7LE7: hiv-1 protease wt (nl4-3) in complex with gs-8374
• 7LE8: hiv-1 protease wt (nl4-3) in complex with pd4 (lr4-23)
• 7LE9: hiv-1 protease wt (nl4-3) in complex with pd5 (lr4-22)
• 7LEA: hiv-1 protease wt (nl4-3) in complex with pu1 (lr3-46)
• 7LEB: hiv-1 protease wt (nl4-3) in complex with pu2 (lr2-79)
• 7LEC: hiv-1 protease wt (nl4-3) in complex with pu3 (lr3-69)
• 7LED: hiv-1 protease wt (nl4-3) in complex with pu4 (lr2-78)
• 7LEE: hiv-1 protease wt (nl4-3) in complex with pu5 (lr4-47)
• 7LEF: hiv-1 protease wt (nl4-3) in complex with pu7 (lr3-67)
• 7LEG: hiv-1 protease wt (nl4-3) in complex with pu8 (lr4-06)
• 7LEH: hiv-1 protease wt (nl4-3) in complex with pu9 (lr2-80)
• 7LEI: hiv-1 protease wt (nl4-3) in complex with pu10 (lr4-07)
• 7TO5: hiv-1 wild type protease with grl-05816a, with c-4 substituted cyclohexane-fused bis-tetrahydrofuran (chf-thf) derivatives as p2- ligand [diastereomer 1] (10.1002/CMDC.202200058 )
• 7TO6: hiv-1 wild type protease with grl-01717a, with c-4 substituted cyclohexane-fused bis-tetrahydrofuran (chf-thf) derivatives as p2- ligand [diastereomer 2] (10.1002/CMDC.202200058 )
• 7UPJ: hiv-1 protease/u101935 complex (10.1021/JM960441M )
• 8HVP: structure at 2.5-angstroms resolution of chemically synthesized human immunodeficiency virus type 1 protease complexed with a hydroxyethylene*-based inhibitor (10.1021/BI00220A023 )
• 9HVP: design, activity and 2.8 angstroms crystal structure of a c2 symmetric inhibitor complexed to hiv-1 protease