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Target
Sequence
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Ki
IC50
Kd
EC50
Rate constants
ΔG°
ΔH°
-TΔS°
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IC50
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rcsb
for Mitogen-activated protein kinase 1
3ERK
: the complex structure of the map kinase erk2/sb220025 (
10.1016/S0969-2126(98)00113-0
)
6Y7W
: fragment kcl_1337 in complex with map kinase p38-alpha (
10.1021/ACS.JMEDCHEM.0C00403
)
6Y7Z
: fragment kcl_914 in complex with map kinase p38-alpha
6Y7X
: fragment kcl_771 in complex with map kinase p38-alpha (
10.1021/ACS.JMEDCHEM.0C00403
)
4LOP
: structural basis of autoactivation of p38 alpha induced by tab1 (tetragonal crystal form) (
10.1038/NSMB.2668
)
4LOO
: structural basis of autoactivation of p38 alpha induced by tab1 (monoclinic crystal form) (
10.1038/NSMB.2668
)
6SOV
: fragments kcl_615 and kcl_802 in complex with map kinase p38-alpha (
10.1021/ACS.JMEDCHEM.0C00403
)
6YCU
: fragment kcl_k777 in complex with map kinase p38-alpha (
10.1021/ACS.JMEDCHEM.0C00403
)
6Y7Y
: fragments kcl_771 and kcl_802 in complex with map kinase p38-alpha (
10.1021/ACS.JMEDCHEM.0C00403
)
1BL7
: the complex structure of the map kinase p38/sb220025 (
10.1016/S0969-2126(98)00113-0
)
6SP9
: fragment kcl802 in complex with map kinase p38-alpha (
10.1021/ACS.JMEDCHEM.0C00403
)
6SPL
: fragment kcl615 in complex with map kinase p38-alpha (
10.1021/ACS.JMEDCHEM.0C00403
)
6Y85
: fragment kcl_1410 in complex with map kinase p38-alpha
6Y82
: fragment kcl_804 in complex with map kinase p38-alpha
6Y81
: fragment kcl_1088 in complex with map kinase p38-alpha (
10.1021/ACS.JMEDCHEM.0C00403
)
6Y80
: fragment kcl_916 in complex with map kinase p38-alpha (
10.1021/ACS.JMEDCHEM.0C00403
)
5O90
: crystal structure of a p38alpha t185g mutant in complex with tab1 peptide. (
10.1128/MCB.00409-17
)
4LOQ
: structural basis of autoactivation of p38 alpha induced by tab1 (tetragonal crystal form with bound sulphate) (
10.1038/NSMB.2668
)
6Y8H
: novel p38-alpha crystal lattice with highly exposed p38/tab1 non- canonical ppi surface.
6YCW
: fragment kcl_k767 in complex with map kinase p38-alpha (
10.1021/ACS.JMEDCHEM.0C00403
)