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Target
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Ki
IC50
Kd
EC50
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ΔH°
-TΔS°
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rcsb
for Tyrosine-protein kinase ZAP-70
1AQ1
: human cyclin dependent kinase 2 complexed with the inhibitor staurosporine (
10.1038/NSB1097-796
)
1BYG
: kinase domain of human c-terminal src kinase (csk) in complex with inhibitor staurosporine (
10.1006/JMBI.1998.2369
)
1E8Z
: structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, ly294002, quercetin, myricetin and staurosporine (
10.1016/S1097-2765(05)00089-4
)
1NVR
: the complex structure of checkpoint kinase chk1/staurosporine (
10.1074/JBC.M201233200
)
1NXK
: crystal structure of staurosporine bound to map kap kinase 2 (
10.1016/S0969-2126(03)00092-3
)
1OKY
: structure of human pdk1 kinase domain in complex with staurosporine (
10.1042/BJ20031119
)
1Q3D
: gsk-3 beta complexed with staurosporine (
10.1016/J.JMB.2003.08.031
)
1QPD
: structural analysis of the lymphocyte-specific kinase lck in complex with non-selective and src family selective kinase inhibitors (
10.1016/S0969-2126(99)80086-0
)
1QPJ
: crystal structure of the lymphocyte-specific kinase lck in complex with staurosporine. (
10.1016/S0969-2126(99)80086-0
)
1SM2
: crystal structure of the phosphorylated interleukin-2 tyrosine kinase catalytic domain (
10.1074/JBC.M400031200
)
1SNU
: crystal structure of the unphosphorylated interleukin-2 tyrosine kinase catalytic domain (
10.1074/JBC.M400031200
)
1STC
: camp-dependent protein kinase, alpha-catalytic subunit in complex with staurosporine (
10.1016/S0969-2126(97)00310-9
)
1U59
: crystal structure of the zap-70 kinase domain in complex with staurosporine (
10.1074/JBC.M407096200
)
1WVY
: crystal structures of kinase domain of dap kinase in complex with small molecular inhibitors
1XBC
: crystal structure of the syk tyrosine kinase domain with staurosporin (
10.1074/JBC.M409792200
)
1XJD
: crystal structure of pkc-theta complexed with staurosporine at 2a resolution (
10.1074/JBC.M409216200
)
1YHS
: crystal structure of pim-1 bound to staurosporine (
10.1074/JBC.M413155200
)
2BUJ
: crystal structure of the human serine-threonine kinase 16 in complex with staurosporine
2CLQ
: structure of mitogen-activated protein kinase kinase kinase 5 (
10.1016/J.STR.2007.08.011
)
2DQ7
: crystal structure of fyn kinase domain complexed with staurosporine (
10.1016/J.BBRC.2006.05.212
)
2GCD
: tao2 kinase domain-staurosporine structure
2HW7
: crystal structure of mnk2-d228g in complex with staurosporine (
10.1038/SJ.EMBOJ.7601285
)
2ITQ
: crystal structure of egfr kinase domain g719s mutation in complex with afn941 (
10.1016/J.CCR.2006.12.017
)
2ITU
: crystal structure of egfr kinase domain l858r mutation in complex with afn941 (
10.1016/J.CCR.2006.12.017
)
2ITW
: crystal structure of egfr kinase domain in complex with afn941 (
10.1016/J.CCR.2006.12.017
)
2NRY
: crystal structure of irak-4 (
10.1016/J.STR.2006.11.001
)
2OIC
: crystal structure of irak4 kinase domain complexed with staurosporine