Affinity DataIC50: 1nMAssay Description:Antagonist activity at human recombinant CCR5 by cell-cell fusion assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of CCR5 by cell-cell fusion inhibition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human recombinant CCR5 by cell-cell fusion assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto
Roche Palo Alto
Affinity DataIC50: 3nM EC50: 1nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto
Roche Palo Alto
Affinity DataIC50: 3nM EC50: >25nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto
Roche Palo Alto
Affinity DataIC50: 3nM EC50: 4nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human recombinant CCR5 by cell-cell fusion assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto
Roche Palo Alto
Affinity DataIC50: 5nM EC50: 2nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human recombinant CCR5 by cell-cell fusion assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Binding affinity at CCR5 receptor by radiolabelled RANTES binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche R&D Center China
Curated by ChEMBL
Roche R&D Center China
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche R&D Center China
Curated by ChEMBL
Roche R&D Center China
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor cotransfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto
Roche Palo Alto
Affinity DataIC50: 8nM EC50: 4nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto
Roche Palo Alto
Affinity DataIC50: 8nM EC50: 1nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Binding affinity at CCR5 receptor by radiolabelled RANTES binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of CCR5 by cell-cell fusion inhibition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche R&D Center China
Curated by ChEMBL
Roche R&D Center China
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto
Roche Palo Alto
Affinity DataIC50: 9nM EC50: 18nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human recombinant CCR5 by cell-cell fusion assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor cotransfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor cotransfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at CCR5 receptor (unknown origin) by radiolabelled RANTES binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of CCR5 by cell-cell fusion inhibition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto
Roche Palo Alto
Affinity DataIC50: 12nM EC50: 97nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair