TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.0370nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.0370nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.0430nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.0490nMAssay Description:Displacement of [3H]DAMGO from mouse brain mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0520nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.0520nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.0750nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.0810nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.0970nMAssay Description:Displacement of [3H]DAMGO from mouse brain mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nM ΔG°: -59.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
Affinity DataKi: 0.109nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse brain membranes without cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.154nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium m...More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.165nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Displacement of [125I] HEAT from human alpha1D adrenergic receptor expressed in Chlorocebus aethiops COS1 cell membranes incubated for 60 mins by liq...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]DPDPE from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.193nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 0.197nMAssay Description:Displacement of [3H]-U-69593 from recombinant human KOR expressed in CHO cell membranes measured after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.211nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain devoid of cerebellumMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair