Affinity DataKi: 1.60nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 211nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 244nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 253nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 293nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 295nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 301nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 304nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 309nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 348nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 495nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 525nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 758nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 926nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.04E+3nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.73E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.82E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.07E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.07E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.16E+3nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.28E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.35E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.39E+3nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.81E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.08E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.22E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.57E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.62E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.67E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.78E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 4.11E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 5.31E+3nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 5.51E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of CYP2D6 (unknown origin) using EOMCC as a substrateMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Sharjah
Curated by ChEMBL
University Of Sharjah
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of c-Raf (unknown origin) in presence of ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of C-terminal FLAG/His-tagged human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus-infected Sf9 cells assessed as reductio...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of C-terminal 6XHis-tagged human recombinant full length HDAC2 (1 to 488 residues) expressed in baculovirus-infected Sf9 cells assessed as...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in baculovirus-infected Sf9 cells assessed as reduction in 7-amino-4-...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by FRET analysisChecked by AuthorMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
University Of Sharjah
Curated by ChEMBL
University Of Sharjah
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of C-terminal His-tagged human recombinant full length HDAC3 (1 to 428 residues)/N-terminal GST-tagged human recombinant NCOR2 (395 to 489...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal GST-tagged/C-terminal His-tagged human recombinant HDAC4 (627 to 1084 residues) expressed in baculovirus-infected Sf9 cells ...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by FRET analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by FRET analysisChecked by AuthorMore data for this Ligand-Target Pair