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Found 211 with Last Name = 'alet' and Initial = 'n'
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM7840(RIVAROXABAN | US8822458, 44 | US8822458, 97)
Affinity DataKi:  0.400nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataKi:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of t-PA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443855(CHEMBL3091517)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443857(CHEMBL3091501)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443846(CHEMBL3091527)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443858(CHEMBL3091502)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443847(CHEMBL3091526)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataIC50:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443844(CHEMBL3091506)
Affinity DataIC50:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443861(CHEMBL3091515)
Affinity DataIC50:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443848(CHEMBL3091525)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443862(CHEMBL3091514)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443869(CHEMBL3091507)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443867(CHEMBL3091509)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443865(CHEMBL3091511)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443864(CHEMBL3091512)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183069(US9150544, 103)
Affinity DataIC50:  1.40nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443845(CHEMBL3091528)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443856(CHEMBL3091503)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443866(CHEMBL3091510)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM182990(US9150544, 24)
Affinity DataIC50:  2nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443860(CHEMBL3091505)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50328705(CHEMBL1270156 | Tanogitran)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443863(CHEMBL3091513)
Affinity DataIC50:  3nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443868(CHEMBL3091508)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443859(CHEMBL3091504)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM182980(US9150544, 14)
Affinity DataIC50:  4nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183016(US9150544, 50)
Affinity DataIC50:  5nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183014(US9150544, 48)
Affinity DataIC50:  6.40nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM182987(US9150544, 21)
Affinity DataIC50:  8nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183012(US9150544, 46)
Affinity DataIC50:  8.40nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM182996(US9150544, 30)
Affinity DataIC50:  12nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443849(CHEMBL3091524)
Affinity DataIC50:  13nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183010(US9150544, 44)
Affinity DataIC50:  14nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM17298(4-[({1-methyl-5-[1-(pyrrolidin-1-ylcarbonyl)cyclop...)
Affinity DataIC50:  15nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183028(US9150544, 62)
Affinity DataIC50:  16nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM182983(US9150544, 17)
Affinity DataIC50:  17nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183058(US9150544, 92)
Affinity DataIC50:  19nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM182977(US9150544, 11)
Affinity DataIC50:  21nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM182979(US9150544, 13)
Affinity DataIC50:  21nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183006(US9150544, 40)
Affinity DataIC50:  22nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183061(US9150544, 95)
Affinity DataIC50:  25nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183019(US9150544, 53)
Affinity DataIC50:  27nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM182975(US9150544, 9)
Affinity DataIC50:  29nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM60667(BDBM183000 | US9150544, 34)
Affinity DataIC50:  32nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM60667(BDBM183000 | US9150544, 34)
Affinity DataIC50:  32nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183045(US9150544, 79)
Affinity DataIC50:  33nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 然 final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
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