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Found 18 with Last Name = 'ammann' and Initial = 'd'
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50028166(CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...)
Affinity DataIC50:  14.6nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human placental CYP19 using androstenedione as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334187(3,4-Difluoro-N-(pyridin-3-yl)benzamide | CHEMBL164...)
Affinity DataIC50:  53.5nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334191(4-Chloro-N-(pyridin-3-yl)benzamide | CHEMBL1645408)
Affinity DataIC50:  65nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50028166(CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334189(4-Cyano-N-(pyridin-3-yl)benzamide | CHEMBL1645412)
Affinity DataIC50:  78nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334192(4-Fluoro-N-(pyridin-3-yl)benzamide | CHEMBL1645407)
Affinity DataIC50:  82nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334190(4-Bromo-N-(pyridin-3-yl)benzamide | CHEMBL1645409)
Affinity DataIC50:  104nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334188(4-Nitro-N-(pyridin-3-yl)benzamide | CHEMBL1645413)
Affinity DataIC50:  145nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334186(2,4,5-trifluoro-N-(pyridin-3-yl)benzamide | CHEMBL...)
Affinity DataIC50:  166nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334187(3,4-Difluoro-N-(pyridin-3-yl)benzamide | CHEMBL164...)
Affinity DataIC50:  5.92E+3nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334189(4-Cyano-N-(pyridin-3-yl)benzamide | CHEMBL1645412)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334191(4-Chloro-N-(pyridin-3-yl)benzamide | CHEMBL1645408)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334192(4-Fluoro-N-(pyridin-3-yl)benzamide | CHEMBL1645407)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334186(2,4,5-trifluoro-N-(pyridin-3-yl)benzamide | CHEMBL...)
Affinity DataIC50:  1.61E+4nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334190(4-Bromo-N-(pyridin-3-yl)benzamide | CHEMBL1645409)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland

Curated by ChEMBL
LigandPNGBDBM50334188(4-Nitro-N-(pyridin-3-yl)benzamide | CHEMBL1645413)
Affinity DataIC50:  2.48E+4nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed