TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central Drug Research Institute
Curated by ChEMBL
Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DNA ligase 1More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Competitive inhibition of human DNA ligase 4 using nicked DNA as substrate by high-throughput fluorescence energy transfer-based DNA joining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Competitive inhibition of human DNA ligase 1 using nicked DNA as substrate by high-throughput fluorescence energy transfer-based DNA joining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Competitive inhibition of human DNA ligase 3 using nicked DNA as substrate by high-throughput fluorescence energy transfer-based DNA joining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Competitive inhibition of human DNA ligase 1 using nicked DNA as substrate by high-throughput fluorescence energy transfer-based DNA joining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Competitive inhibition of human DNA ligase 3 using nicked DNA as substrate by high-throughput fluorescence energy transfer-based DNA joining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Uncompetitive inhibition of human DNA ligase 1 using nicked DNA as substrate by high-throughput fluorescence energy transfer-based DNA joining assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+4nMAssay Description:Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 3.64E+4nMAssay Description:Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 5.11E+4nMAssay Description:Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.66E+4nMAssay Description:Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.17E+4nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.79E+4nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.86E+5nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.95E+5nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.08E+5nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.24E+5nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+5nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.56E+5nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.82E+5nMAssay Description:Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.82E+5nMAssay Description:Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.22E+6nMAssay Description:Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Affinity DataKd: 8.95E+4nMAssay Description:Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMAssay Description:Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysisMore data for this Ligand-Target Pair
Affinity DataKd: 6.00E+3nMAssay Description:Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysisMore data for this Ligand-Target Pair
Affinity DataKd: 4.60E+3nMAssay Description:Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.03E+5nMAssay Description:Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysisMore data for this Ligand-Target Pair
Affinity DataKd: 4.40E+4nMAssay Description:Binding affinity to recombinant rat calcium loaded S100-B by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 5.00E+4nMAssay Description:Binding affinity to recombinant rat calcium loaded S100-B by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysisMore data for this Ligand-Target Pair