Affinity DataIC50: 0.600nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Tested in vitro for inhibition of Angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Tested in vitro for inhibition of Angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Tested in vitro for inhibition of Angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme isolated from rabbit lung extract.More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme isolated from rabbit lung extract.More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzyme (ACE) isolated from rabbit lung extract using hippuryl-L-histidyl-L-leucine (HHL...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against angiotensin converting enzyme (ACE) in rat was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of purified rat kidney Neutral endopeptidase.More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzyme (ACE) isolated from rabbit lung extract using hippuryl-L-histidyl-L-leucine (HHL...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Neutral Endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Neutral Endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro inhibitory activity against angiotensin converting enzyme (ACE) in rat was determinedMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme isolated from rabbit lung extract.More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:In vitro inhibitory activity against angiotensin converting enzyme (ACE) in rat was determinedMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme isolated from rabbit lung extract.More data for this Ligand-Target Pair