Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Chemveda Life Sciences India
Curated by ChEMBL
Chemveda Life Sciences India
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human CLK1 (130 to end residues) using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of [gamma33P-ATP] by...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Chemveda Life Sciences India
Curated by ChEMBL
Chemveda Life Sciences India
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human CLK1 (130 to end residues) using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of [gamma33P-ATP] by...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HClMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Chemveda Life Sciences India
Curated by ChEMBL
Chemveda Life Sciences India
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human CLK4 (128 to end residues) using YRRAAVPPSPSLSRHSSPHQS(p)EDEEE as substrate incubated for 40 mins in presence of [gam...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Chemveda Life Sciences India
Curated by ChEMBL
Chemveda Life Sciences India
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human CLK2 (138 to end residues) using YRRAAVPPSPSLSRHSSPHQS(p)EDEEE as substrate incubated for 40 mins in presence of [gam...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human PIM1 expressed in bacterial expression system using histone H1 as substrate measured after 30 mins in presence of ATP...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Paris-Sud University
Curated by ChEMBL
Paris-Sud University
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Universite£? De Rennes 1
Curated by ChEMBL
Universite£? De Rennes 1
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant GST-tagged DYRK2 using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Universite£? De Rennes 1
Curated by ChEMBL
Universite£? De Rennes 1
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant GST-tagged DYRK2 using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in bacterial expression system using histone H1 as substrate in presence of ATP at measured after ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Universite£? De Rennes 1
Curated by ChEMBL
Universite£? De Rennes 1
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant GST-tagged DYRK2 using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrate measured after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Universite£? De Rennes 1
Curated by ChEMBL
Universite£? De Rennes 1
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant GST-tagged DYRK2 using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Universite£? De Rennes 1
Curated by ChEMBL
Universite£? De Rennes 1
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant GST-tagged DYRK2 using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HClMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human HASPIN (470 to 798 residues) expressed in bacterial expression system in presence of ATP by kinomescan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Chemveda Life Sciences India
Curated by ChEMBL
Chemveda Life Sciences India
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Universite£? De Rennes 1
Curated by ChEMBL
Universite£? De Rennes 1
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant GST-tagged DYRK2 using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMpH: 7.0 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Binding affinity to partial length human BRD9 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant human Haspin (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate measur...More data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair