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Found 443 with Last Name = 'bellevergue' and Initial = 'p'
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2685(3-(1H-indol-3-yl)-4-{1-[2-(piperidin-2-yl)ethyl]-1...)
Affinity DataIC50:  5nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
Affinity DataIC50:  10nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2694(3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl...)
Affinity DataIC50:  13nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
Affinity DataIC50:  26nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2692(3-(1H-indol-3-yl)-4-{1-[(1-methylpiperidin-3-yl)me...)
Affinity DataIC50:  45nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2686(3-(1H-indol-3-yl)-4-{1-[3-(piperazin-1-yl)propyl]-...)
Affinity DataIC50:  52nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2693(3-(1H-indol-3-yl)-4-{1-[3-(morpholin-4-yl)propyl]-...)
Affinity DataIC50:  70nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140907(US8912224, 345)
Affinity DataIC50:  70nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2690(3-(1-{2-[(dimethylamino)methyl]propyl}-1H-indol-3-...)
Affinity DataIC50:  80nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140915(US8912224, 353)
Affinity DataIC50:  92nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140616(US8912224, 45)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140727(US8912224, 159)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140619(US8912224, 48)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140620(US8912224, 49)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140629(US8912224, 59)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140630(US8912224, 60 | US8912224, 61)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140874(US8912224, 311)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140875(US8912224, 312)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140877(US8912224, 314)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140879(US8912224, 317)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140880(US8912224, 318)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140888(US8912224, 326)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140618(US8912224, 47)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM47064(US8912224, 57)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the PBX Calcium Assay Kit from BD (Becton, Dickinson and Company) with...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2682(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-[1...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Laboratoires Glaxo

LigandPNGBDBM2583(3,4-Bis(3-indolyl)-1H-pyrrole-2,5-dione | 3,4-bis(...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140830(US8912224, 266)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140810(US8912224, 245)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140586(US8912224, 15)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140587(US8912224, 16)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140590(US8912224, 19)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140592(US8912224, 21)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140595(US8912224, 24)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140600(US8912224, 29)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140607(US8912224, 36)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140739(US8912224, 171)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140772(US8912224, 204)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140778(US8912224, 210)
Affinity DataIC50:  100nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140913(US8912224, 351)
Affinity DataIC50:  110nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140912(US8912224, 350)
Affinity DataIC50:  120nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140916(US8912224, 354)
Affinity DataIC50:  160nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140908(US8912224, 346)
Affinity DataIC50:  170nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform(Oryctolagus cuniculus (rabbit))
Laboratoires Glaxo

LigandPNGBDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
Affinity DataIC50:  180nMAssay Description:The activity of PK is measured by its ability to transfer from [gamma-32P]ATP to phosphorylase b.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140928(US8912224, 366)
Affinity DataIC50:  180nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140608(US8912224, 37)
Affinity DataIC50:  200nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140613(US8912224, 42)
Affinity DataIC50:  200nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140615(US8912224, 44)
Affinity DataIC50:  200nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140617(US8912224, 46)
Affinity DataIC50:  200nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/calcium exchanger 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM140621(US8912224, 50)
Affinity DataIC50:  200nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In DepthDetails US Patent
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