TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL-1-induced IL-6 production after 24 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 0.510nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of TAMRA-labeled dexamethasone from glucocorticoid receptor (unknown origin) by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]-cDPPO from human Ephx2 by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of TAMRA-labeled dexamethasone from glucocorticoid receptor (unknown origin) by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of TAMRA-labeled dexamethasone from glucocorticoid receptor (unknown origin) by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of JNK2alpha2 (unknown origin) by by exchange curve binding kinetic analysisMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Displacement of TAMRA-labeled dexamethasone from glucocorticoid receptor (unknown origin) by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Binding affinity towards glucocorticoid receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Transrepression activity at glucocorticoid receptor in human fibroblasts assessed as inhibition of IL-1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of TAMRA-labeled dexamethasone from glucocorticoid receptor (unknown origin) by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of TAMRA-labeled dexamethasone from glucocorticoid receptor (unknown origin) by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]-cDPPO from human Ephx2 by cell-based assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Transrepression activity at glucocorticoid receptor in human fibroblasts assessed as inhibition of IL-1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Binding affinity towards glucocorticoid receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL-1-induced IL-6 production after 24 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Binding affinity towards glucocorticoid receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Binding affinity towards glucocorticoid receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human Ephx2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Transrepression activity at glucocorticoid receptor in human fibroblasts assessed as inhibition of IL-1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals Inc
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...More data for this Ligand-Target Pair