Affinity DataKi: 250nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Second order rate constant for the in vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Inhibitory activity agaiinst HLE at 10 min (48 mM conc)More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 6.10E+3nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 4.30E+4nMAssay Description:In vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
TargetChymotrypsin-like elastase family member 1/2A(Sus scrofa (Pig))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
TargetChymotrypsin-like elastase family member 1/2A(Sus scrofa (Pig))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against Human Leukocyte ElastaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
TargetChymotrypsinogen A(Bos taurus (bovine))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of alpha-chymotrypsin enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
TargetChymotrypsin-like elastase family member 1/2A(Sus scrofa (Pig))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of Porcine pancreatic elastase (PPE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
TargetChymotrypsinogen A(Bos taurus (bovine))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of bovine alpha-chymotrypsin (ChT)More data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of TrypsinMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: <4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory concentration which is required to cause 50% inhibition of human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair